Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers
Herein, we investigated the effects of a ballet class on the kinetic profiles of creatine kinase (CK) and lactate dehydrogenase (LDH) activities, cytokines, complement component 3 (C3), and the concentrations of immunoglobulin (Ig), IgA and IgM, in ballerinas. We also verified neutrophil death and R...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2014/846021 |
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| author | Leandro da Silva Borges José Ricardo Bortolon Vinicius Coneglian Santos Nivaldo Ribeiro de Moura Alexandre Dermargos Maria Fernanda Cury-Boaventura Renata Gorjão Tania Cristina Pithon-Curi Elaine Hatanaka |
| author_facet | Leandro da Silva Borges José Ricardo Bortolon Vinicius Coneglian Santos Nivaldo Ribeiro de Moura Alexandre Dermargos Maria Fernanda Cury-Boaventura Renata Gorjão Tania Cristina Pithon-Curi Elaine Hatanaka |
| author_sort | Leandro da Silva Borges |
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| description | Herein, we investigated the effects of a ballet class on the kinetic profiles of creatine kinase (CK) and lactate dehydrogenase (LDH) activities, cytokines, complement component 3 (C3), and the concentrations of immunoglobulin (Ig), IgA and IgM, in ballerinas. We also verified neutrophil death and ROS release. Blood samples were taken from 13 dancers before, immediately after, and 18 hours after a ballet class. The ballet class increased the plasma activities of CK-total (2.0-fold) immediately after class, while the activities of CK-cardiac muscle (1.0-fold) and LDH (3.0-fold) were observed to increase 18 hours after the class. Levels of the TNF-α, IL-1β, IgG, and IgA were not affected under the study conditions. The exercise was found to induce neutrophil apoptosis (6.0-fold) 18 hours after the ballet class. Additionally, immediately after the ballet class, the neutrophils from the ballerinas were found to be less responsive to PMA stimulus. Conclusion. Ballet class was found to result in inflammation in dancers. The inflammation caused by the ballet class remained for 18 hours after the exercise. These findings are important in preventing the development of chronic lesions that are commonly observed in dancers, such as those with arthritis and synovitis. |
| format | Article |
| id | doaj-art-15aa54da7cf04676bb8361542f67599d |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-15aa54da7cf04676bb8361542f67599d2025-02-03T05:59:28ZengWileyMediators of Inflammation0962-93511466-18612014-01-01201410.1155/2014/846021846021Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet DancersLeandro da Silva Borges0José Ricardo Bortolon1Vinicius Coneglian Santos2Nivaldo Ribeiro de Moura3Alexandre Dermargos4Maria Fernanda Cury-Boaventura5Renata Gorjão6Tania Cristina Pithon-Curi7Elaine Hatanaka8Instituto de Ciências da Atividade Física e Esportes, Universidade Cruzeiro do Sul, Rua Galvão Bueno 868, 13°Andar, Bloco B, 01506-000 Liberdade, São Paulo, SP, BrazilInstituto de Ciências da Atividade Física e Esportes, Universidade Cruzeiro do Sul, Rua Galvão Bueno 868, 13°Andar, Bloco B, 01506-000 Liberdade, São Paulo, SP, BrazilInstituto de Ciências da Atividade Física e Esportes, Universidade Cruzeiro do Sul, Rua Galvão Bueno 868, 13°Andar, Bloco B, 01506-000 Liberdade, São Paulo, SP, BrazilInstituto de Ciências da Atividade Física e Esportes, Universidade Cruzeiro do Sul, Rua Galvão Bueno 868, 13°Andar, Bloco B, 01506-000 Liberdade, São Paulo, SP, BrazilInstituto de Ciências da Atividade Física e Esportes, Universidade Cruzeiro do Sul, Rua Galvão Bueno 868, 13°Andar, Bloco B, 01506-000 Liberdade, São Paulo, SP, BrazilInstituto de Ciências da Atividade Física e Esportes, Universidade Cruzeiro do Sul, Rua Galvão Bueno 868, 13°Andar, Bloco B, 01506-000 Liberdade, São Paulo, SP, BrazilInstituto de Ciências da Atividade Física e Esportes, Universidade Cruzeiro do Sul, Rua Galvão Bueno 868, 13°Andar, Bloco B, 01506-000 Liberdade, São Paulo, SP, BrazilInstituto de Ciências da Atividade Física e Esportes, Universidade Cruzeiro do Sul, Rua Galvão Bueno 868, 13°Andar, Bloco B, 01506-000 Liberdade, São Paulo, SP, BrazilInstituto de Ciências da Atividade Física e Esportes, Universidade Cruzeiro do Sul, Rua Galvão Bueno 868, 13°Andar, Bloco B, 01506-000 Liberdade, São Paulo, SP, BrazilHerein, we investigated the effects of a ballet class on the kinetic profiles of creatine kinase (CK) and lactate dehydrogenase (LDH) activities, cytokines, complement component 3 (C3), and the concentrations of immunoglobulin (Ig), IgA and IgM, in ballerinas. We also verified neutrophil death and ROS release. Blood samples were taken from 13 dancers before, immediately after, and 18 hours after a ballet class. The ballet class increased the plasma activities of CK-total (2.0-fold) immediately after class, while the activities of CK-cardiac muscle (1.0-fold) and LDH (3.0-fold) were observed to increase 18 hours after the class. Levels of the TNF-α, IL-1β, IgG, and IgA were not affected under the study conditions. The exercise was found to induce neutrophil apoptosis (6.0-fold) 18 hours after the ballet class. Additionally, immediately after the ballet class, the neutrophils from the ballerinas were found to be less responsive to PMA stimulus. Conclusion. Ballet class was found to result in inflammation in dancers. The inflammation caused by the ballet class remained for 18 hours after the exercise. These findings are important in preventing the development of chronic lesions that are commonly observed in dancers, such as those with arthritis and synovitis.http://dx.doi.org/10.1155/2014/846021 |
| spellingShingle | Leandro da Silva Borges José Ricardo Bortolon Vinicius Coneglian Santos Nivaldo Ribeiro de Moura Alexandre Dermargos Maria Fernanda Cury-Boaventura Renata Gorjão Tania Cristina Pithon-Curi Elaine Hatanaka Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers Mediators of Inflammation |
| title | Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers |
| title_full | Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers |
| title_fullStr | Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers |
| title_full_unstemmed | Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers |
| title_short | Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers |
| title_sort | chronic inflammation and neutrophil activation as possible causes of joint diseases in ballet dancers |
| url | http://dx.doi.org/10.1155/2014/846021 |
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