eEF2K is a poor prognostic factor and novel molecular target in pancreatic cancer: regulating tumor growth and progression via the tumor microenvironment

eEF2K is a poor prognostic factor and novel molecular target in pancreatic cancer: regulating tumor growth and progression via the tumor microenvironment

Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers, with an average survival time of only six months following diagnosis, even with currently available therapies. Thus, PDAC represents a significant therapeutic challenge, necessitating a deeper understanding of its bi...

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Main Authors: Didem Karakas, Ahmed Ashour, Hamada Ahmed Mokhlis, Nermin Kahraman, Recep Bayraktar, Sayra Dilmac, Nashwa N. Kabil, Mumin Alper Erdogan, Egemen Dere, Engin Ulukaya, Bulent Ozpolat
Format: Article
Language:English
Published: Nature Publishing Group 2025-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07803-w
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