Roles of the rpoEc-chrR-chrA operon in superoxide tolerance and β-lactam susceptibility of Stenotrophomonas maltophilia

Roles of the rpoEc-chrR-chrA operon in superoxide tolerance and β-lactam susceptibility of Stenotrophomonas maltophilia

IntroductionThe rpoE-chrR pair is a regulatory system used by photosynthetic microorganisms to overcome singlet oxygen stress. rpoE and chrR encode the sigma factor σE and anti-sigma factor ChrR, respectively. Stenotrophomonas maltophilia, an opportunistic pathogen, is a multidrug-resistant gram-neg...

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Main Authors: Ren-Hsuan Ku, Hsu-Feng Lu, Li-Hua Li, Ting-Yu Yeh, Yi-Tsung Lin, Tsuey-Ching Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Stenotrophomonas maltophilia
singlet oxygen
β-lactam susceptibility
oxidative stress
sigma factor
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1492008/full
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