Alternate Grainy head isoforms regulate Drosophila midgut intestinal stem cell differentiation

Abstract Regeneration of the Drosophila midgut epithelium depends upon differential expression of transcription factors in intestinal stem cells and their progeny. The grainy head locus produces multiple splice forms that result in production of two classes of transcription factor, designated Grh.O...

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Bibliographic Details
Main Authors: Nicole Dominado, Rachel Ye, Franca Casagranda, James Heaney, Nicole A. Siddall, Helen E. Abud, Gary R. Hime
Format: Article
Language:English
Published: Nature Publishing Group 2025-04-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02496-8
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