Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and gut health markers in patients with irritable bowel syndrome—A randomized, double-blind, placebo-controlled trial

Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and gut health markers in patients with irritable bowel syndrome—A randomized, double-blind, placebo-controlled trial

IntroductionIrritable bowel syndrome (IBS) is the most prevalent functional bowel disorder impacting around 5%−10% of the general population worldwide. The pathogenesis remains unclear, however alterations in gut-brain axis play a critical role. We aimed to investigate the therapeutic potential of a...

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Main Authors: Adrianna Wierzbicka, Barbara Khaidakov, Oliwia Zakerska-Banaszak, Paulina Andrzejewska, Alina Baturo, Paulina Kowalczyk, Krzysztof Lemke, Agnieszka Dobrowolska, Marzena Skrzypczak-Zielinska, Dorota Mankowska-Wierzbicka
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Nutrition
Subjects:
irritable bowel syndrome
dietary intervention
probiotics
fiber
polyphenols
quality of life
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1603011/full
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