TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells

TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells

Transient receptor potential melastatin‐4 channel (TRPM4) dysregulation contributes to heart conditions, immune diseases, and cervical and prostate cancer. Up to now, the involvement of TRPM4 in colorectal cancer (CRC) pathophysiology remains unknown. Here, we investigated tumor tissue microarrays f...

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Bibliographic Details
Main Authors: Sven Kappel, Paulina Stokłosa, Barbara Hauert, Daniela Ross‐Kaschitza, Anna Borgström, Roland Baur, José A. Galván, Inti Zlobec, Christine Peinelt
Format: Article
Language:English
Published: Wiley 2019-11-01
Series:Molecular Oncology
Subjects:
cancer hallmarks
cell cycle analysis
colorectal cancer
CRISPR/cas9
TRPM4
tumor buds
Online Access:https://doi.org/10.1002/1878-0261.12566
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