Tryptophan-induced transcriptomic changes in the European Seabass are highly dependent on neuroendocrine-immune conditions

Tryptophan-induced transcriptomic changes in the European Seabass are highly dependent on neuroendocrine-immune conditions

Abstract In European seabass (Dicentrarchus labrax), dietary tryptophan (TRP) surplus has a notable modulatory effect on the hypothalamic–pituitary–interrenal axis under chronic stress and acute inflammation, affecting cortisol levels and neuroendocrine- and immune-related gene expression. A transcr...

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Bibliographic Details
Main Authors: Diogo Peixoto, Inês Carvalho, Diego Robledo, Marina Machado, Patricia Pereiro, Antonio Figueras, Rita Azeredo, Benjamín Costas
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Immunonutrition
Tryptophan supplementation
RNA-seq
Confinement stress
Inflammation
Online Access:https://doi.org/10.1038/s41598-025-01079-y
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