Circadian Alterations in Brain Metabolism Linked to Cognitive Deficits During Hepatic Ischemia-Reperfusion Injury Using [<sup>1</sup>H-<sup>13</sup>C]-NMR Metabolomics

Circadian Alterations in Brain Metabolism Linked to Cognitive Deficits During Hepatic Ischemia-Reperfusion Injury Using [<sup>1</sup>H-<sup>13</sup>C]-NMR Metabolomics

<b>Background</b>: Hepatic ischemia-reperfusion injury (HIRI) is known to affect cognitive functions, with particular concern for its impact on brain metabolic dynamics. Circadian rhythms, as a crucial mechanism for internal time regulation within organisms, significantly influence metab...

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Bibliographic Details
Main Authors: Yijing Li, Yanbo Liu, Zhigang He, Zhixiao Li, Hongbing Xiang
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomedicines
Subjects:
hepatic ischemia-reperfusion injury
cognitive deficits
circadian alterations
NMR metabolomics
brain metabolism
Online Access:https://www.mdpi.com/2227-9059/12/11/2536
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