Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature Review
In patients with haematologic malignancies such as lymphoma and leukaemia, significant increases in survival have been seen, due to advances in treatment strategies. However, long-term survivors of these cancers still remain at a higher risk of developing second cancers during their lifetime, espec...
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| Format: | Article |
| Language: | English |
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European Medical Journal
2022-03-01
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| Series: | European Medical Journal Oncology |
| Online Access: | https://www.emjreviews.com/oncology/article/ewings-sarcoma-of-the-lung-as-a-second-malignancy-in-long-term-survivor-of-childhood-hodgkins-lymphoma-a-rare-case-report-and-literature-review-j190121/ |
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| author | Sumit Bharti Deepak Bhasin Gautam Goyal Priya Sharma |
| author_facet | Sumit Bharti Deepak Bhasin Gautam Goyal Priya Sharma |
| author_sort | Sumit Bharti |
| collection | DOAJ |
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In patients with haematologic malignancies such as lymphoma and leukaemia, significant increases in survival have been seen, due to advances in treatment strategies. However, long-term survivors of these cancers still remain at a higher risk of developing second cancers during their lifetime, especially in the fourth decade. It is well known that immunodeficiency after radiotherapy, chemotherapy, or haematopoietic stem cell transplantation impairs the antitumour activity of the innate and adaptive immune systems, predisposing the immune system to fail to detect and eliminate newly mutated cells. Literature shows evidence of various malignancies in these survivors, including sarcomas; breast cancers; mesothelioma; and solid secondary malignancies like breast cancer, thyroid cancer, and bone or soft tissue sarcoma. Here, the author reports a case of development of Ewing’s sarcoma of the lung in an adult who is a long-term survivor of Hodgkin’s lymphoma. |
| format | Article |
| id | doaj-art-15917c48e41a4b879fd74432148167e0 |
| institution | Kabale University |
| issn | 2054-619X |
| language | English |
| publishDate | 2022-03-01 |
| publisher | European Medical Journal |
| record_format | Article |
| series | European Medical Journal Oncology |
| spelling | doaj-art-15917c48e41a4b879fd74432148167e02025-01-16T16:43:15ZengEuropean Medical JournalEuropean Medical Journal Oncology2054-619X2022-03-01949910.33590/emj/21-00201Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature ReviewSumit Bharti0Deepak Bhasin1Gautam Goyal2Priya Sharma3Respiratory Medicine, Max Superspeciality Hospital, Mohali, IndiaDepartment of Critical Care, Max Superspeciality Hospital, Mohali, IndiaMedical Oncology, Max Superspeciality Hospital, Mohali, IndiaDepartment of Pulmonary Medicine, All India Institute of Medical Sciences, Patna, India In patients with haematologic malignancies such as lymphoma and leukaemia, significant increases in survival have been seen, due to advances in treatment strategies. However, long-term survivors of these cancers still remain at a higher risk of developing second cancers during their lifetime, especially in the fourth decade. It is well known that immunodeficiency after radiotherapy, chemotherapy, or haematopoietic stem cell transplantation impairs the antitumour activity of the innate and adaptive immune systems, predisposing the immune system to fail to detect and eliminate newly mutated cells. Literature shows evidence of various malignancies in these survivors, including sarcomas; breast cancers; mesothelioma; and solid secondary malignancies like breast cancer, thyroid cancer, and bone or soft tissue sarcoma. Here, the author reports a case of development of Ewing’s sarcoma of the lung in an adult who is a long-term survivor of Hodgkin’s lymphoma.https://www.emjreviews.com/oncology/article/ewings-sarcoma-of-the-lung-as-a-second-malignancy-in-long-term-survivor-of-childhood-hodgkins-lymphoma-a-rare-case-report-and-literature-review-j190121/ |
| spellingShingle | Sumit Bharti Deepak Bhasin Gautam Goyal Priya Sharma Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature Review European Medical Journal Oncology |
| title | Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature Review |
| title_full | Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature Review |
| title_fullStr | Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature Review |
| title_full_unstemmed | Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature Review |
| title_short | Ewing’s Sarcoma of the Lung as a Second Malignancy in Long-Term Survivor of Childhood Hodgkin’s Lymphoma: A Rare Case Report and Literature Review |
| title_sort | ewing s sarcoma of the lung as a second malignancy in long term survivor of childhood hodgkin s lymphoma a rare case report and literature review |
| url | https://www.emjreviews.com/oncology/article/ewings-sarcoma-of-the-lung-as-a-second-malignancy-in-long-term-survivor-of-childhood-hodgkins-lymphoma-a-rare-case-report-and-literature-review-j190121/ |
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