Effectiveness of Laboratory Parameters as Morbidity and Mortality Indicators in Patients with Coronavirus Disease-2019 Admitted to the Intensive Care Unit
Objective:Laboratory parameters may predict the severity and mortality of coronavirus disease-2019 (COVID-19). We investigated the relationship of laboratory findings obtained at admission and 72nd hour and mortality and morbidity of patients with pneumonia who were treated in two intensive care uni...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayinevi
2021-12-01
|
| Series: | Türk Yoğun Bakim Derneği Dergisi |
| Subjects: | |
| Online Access: |
http://www.turkishjic.org/archives/archive-detail/article-preview/effectiveness-of-laboratory-parameters-as-morbidit/47543
|
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849308672055836672 |
|---|---|
| author | Leyla Kazancıoğlu Başar Erdivanlı Hızır Kazdal Abdullah Özdemir Tolga Koyuncu Ayşe Hızal Asiye Özdemir İlkay Bahçeci Şule Batcık Tahir Ersöz |
| author_facet | Leyla Kazancıoğlu Başar Erdivanlı Hızır Kazdal Abdullah Özdemir Tolga Koyuncu Ayşe Hızal Asiye Özdemir İlkay Bahçeci Şule Batcık Tahir Ersöz |
| author_sort | Leyla Kazancıoğlu |
| collection | DOAJ |
| description | Objective:Laboratory parameters may predict the severity and mortality of coronavirus disease-2019 (COVID-19). We investigated the relationship of laboratory findings obtained at admission and 72nd hour and mortality and morbidity of patients with pneumonia who were treated in two intensive care units.Materials and Methods:Chart data of 75 patients (March-May 2020) were retrospectively analysed. Patient characteristics and laboratory parameters were compared according to the presence of COVID-19 and mortality. Patients with COVID-19 were compared according to mortality and gender.Results:The mean patient age was 74.7±11.3 years. COVID-19 positivity was not associated with marked differences in laboratory values. Lung disease, bedridden status, worse renal function scores, and high C-reactive protein level was more often observed in non-survivors (p<0.05). A decline in D-dimer level was more apparent in survivors; the increase in ferritin and neutrophillymphocyte ratio was more apparent in non-survivors (not significant). Among patients with COVID- 19, women had higher mean platelet volume than men (p=0.033). The rise in ferritin level was more pronounced in men, whereas the rise in neutrophil-lymphocyte ratio and platelet-lymphocyte ratio was higher in women.Conclusion:In this geriatric cohort, chronic lung disease and bedridden status were the main determinants of mortality. Moreover, different patterns of inflammatory markers may help predict the severity of COVID-19. |
| format | Article |
| id | doaj-art-1590ef2cfcf94752bbb09937064a35d0 |
| institution | Kabale University |
| issn | 2146-6416 2147-267X |
| language | English |
| publishDate | 2021-12-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Türk Yoğun Bakim Derneği Dergisi |
| spelling | doaj-art-1590ef2cfcf94752bbb09937064a35d02025-08-20T03:54:24ZengGalenos YayineviTürk Yoğun Bakim Derneği Dergisi2146-64162147-267X2021-12-01191334310.4274/tybd.galenos.2021.0591413049054Effectiveness of Laboratory Parameters as Morbidity and Mortality Indicators in Patients with Coronavirus Disease-2019 Admitted to the Intensive Care UnitLeyla Kazancıoğlu0Başar Erdivanlı1Hızır Kazdal2Abdullah Özdemir3Tolga Koyuncu4Ayşe Hızal5Asiye Özdemir6İlkay Bahçeci7Şule Batcık8Tahir Ersöz9 Recep Tayyip Erdoğan University Faculty of Medicine, Department of Anesthesiology and Reanimation, Rize, Turkey Recep Tayyip Erdoğan University Faculty of Medicine, Department of Anesthesiology and Reanimation, Rize, Turkey Recep Tayyip Erdoğan University Faculty of Medicine, Department of Anesthesiology and Reanimation, Rize, Turkey Recep Tayyip Erdoğan University Faculty of Medicine, Department of Anesthesiology and Reanimation, Rize, Turkey Recep Tayyip Erdoğan University Faculty of Medicine, Department of Anesthesiology and Reanimation, Rize, Turkey Recep Tayyip Erdoğan University Faculty of Medicine, Department of Anesthesiology and Reanimation, Rize, Turkey Recep Tayyip Erdoğan University Faculty of Medicine, Department of Anesthesiology and Reanimation, Rize, Turkey Recep Tayyip Erdoğan University Faculty of Medicine, Department of Medical Microbiology and Clinical Microbiology, Rize, Turkey Recep Tayyip Erdoğan University Faculty of Medicine, Department of Anesthesiology and Reanimation, Rize, Turkey Recep Tayyip Erdoğan University Faculty of Medicine, Department of Anesthesiology and Reanimation, Rize, Turkey Objective:Laboratory parameters may predict the severity and mortality of coronavirus disease-2019 (COVID-19). We investigated the relationship of laboratory findings obtained at admission and 72nd hour and mortality and morbidity of patients with pneumonia who were treated in two intensive care units.Materials and Methods:Chart data of 75 patients (March-May 2020) were retrospectively analysed. Patient characteristics and laboratory parameters were compared according to the presence of COVID-19 and mortality. Patients with COVID-19 were compared according to mortality and gender.Results:The mean patient age was 74.7±11.3 years. COVID-19 positivity was not associated with marked differences in laboratory values. Lung disease, bedridden status, worse renal function scores, and high C-reactive protein level was more often observed in non-survivors (p<0.05). A decline in D-dimer level was more apparent in survivors; the increase in ferritin and neutrophillymphocyte ratio was more apparent in non-survivors (not significant). Among patients with COVID- 19, women had higher mean platelet volume than men (p=0.033). The rise in ferritin level was more pronounced in men, whereas the rise in neutrophil-lymphocyte ratio and platelet-lymphocyte ratio was higher in women.Conclusion:In this geriatric cohort, chronic lung disease and bedridden status were the main determinants of mortality. Moreover, different patterns of inflammatory markers may help predict the severity of COVID-19. http://www.turkishjic.org/archives/archive-detail/article-preview/effectiveness-of-laboratory-parameters-as-morbidit/47543 covid-19pneumoniaintensive care unitmorbiditymortalitygeriatrics |
| spellingShingle | Leyla Kazancıoğlu Başar Erdivanlı Hızır Kazdal Abdullah Özdemir Tolga Koyuncu Ayşe Hızal Asiye Özdemir İlkay Bahçeci Şule Batcık Tahir Ersöz Effectiveness of Laboratory Parameters as Morbidity and Mortality Indicators in Patients with Coronavirus Disease-2019 Admitted to the Intensive Care Unit Türk Yoğun Bakim Derneği Dergisi covid-19 pneumonia intensive care unit morbidity mortality geriatrics |
| title | Effectiveness of Laboratory Parameters as Morbidity and Mortality Indicators in Patients with Coronavirus Disease-2019 Admitted to the Intensive Care Unit |
| title_full | Effectiveness of Laboratory Parameters as Morbidity and Mortality Indicators in Patients with Coronavirus Disease-2019 Admitted to the Intensive Care Unit |
| title_fullStr | Effectiveness of Laboratory Parameters as Morbidity and Mortality Indicators in Patients with Coronavirus Disease-2019 Admitted to the Intensive Care Unit |
| title_full_unstemmed | Effectiveness of Laboratory Parameters as Morbidity and Mortality Indicators in Patients with Coronavirus Disease-2019 Admitted to the Intensive Care Unit |
| title_short | Effectiveness of Laboratory Parameters as Morbidity and Mortality Indicators in Patients with Coronavirus Disease-2019 Admitted to the Intensive Care Unit |
| title_sort | effectiveness of laboratory parameters as morbidity and mortality indicators in patients with coronavirus disease 2019 admitted to the intensive care unit |
| topic | covid-19 pneumonia intensive care unit morbidity mortality geriatrics |
| url |
http://www.turkishjic.org/archives/archive-detail/article-preview/effectiveness-of-laboratory-parameters-as-morbidit/47543
|
| work_keys_str_mv | AT leylakazancıoglu effectivenessoflaboratoryparametersasmorbidityandmortalityindicatorsinpatientswithcoronavirusdisease2019admittedtotheintensivecareunit AT basarerdivanlı effectivenessoflaboratoryparametersasmorbidityandmortalityindicatorsinpatientswithcoronavirusdisease2019admittedtotheintensivecareunit AT hızırkazdal effectivenessoflaboratoryparametersasmorbidityandmortalityindicatorsinpatientswithcoronavirusdisease2019admittedtotheintensivecareunit AT abdullahozdemir effectivenessoflaboratoryparametersasmorbidityandmortalityindicatorsinpatientswithcoronavirusdisease2019admittedtotheintensivecareunit AT tolgakoyuncu effectivenessoflaboratoryparametersasmorbidityandmortalityindicatorsinpatientswithcoronavirusdisease2019admittedtotheintensivecareunit AT aysehızal effectivenessoflaboratoryparametersasmorbidityandmortalityindicatorsinpatientswithcoronavirusdisease2019admittedtotheintensivecareunit AT asiyeozdemir effectivenessoflaboratoryparametersasmorbidityandmortalityindicatorsinpatientswithcoronavirusdisease2019admittedtotheintensivecareunit AT ilkaybahceci effectivenessoflaboratoryparametersasmorbidityandmortalityindicatorsinpatientswithcoronavirusdisease2019admittedtotheintensivecareunit AT sulebatcık effectivenessoflaboratoryparametersasmorbidityandmortalityindicatorsinpatientswithcoronavirusdisease2019admittedtotheintensivecareunit AT tahirersoz effectivenessoflaboratoryparametersasmorbidityandmortalityindicatorsinpatientswithcoronavirusdisease2019admittedtotheintensivecareunit |