Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Prospective Cohort Study
Background. Hypotension and bradycardia are the most common complications associated with spinal anesthesia and more common in patients with a history of hypertension. Regular use of antihypertensive medications can prevent these complications. The occurrence of hypotension under spinal anesthesia a...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Anesthesiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2021/8891252 |
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| author | Leake Gebrargs Bereket Gebremeskel Bacha Aberra Assefa Hika Yusuf Yimer Misrak Weldeyohannes Suleiman Jemal Degena Behrey Abere Tilahun |
| author_facet | Leake Gebrargs Bereket Gebremeskel Bacha Aberra Assefa Hika Yusuf Yimer Misrak Weldeyohannes Suleiman Jemal Degena Behrey Abere Tilahun |
| author_sort | Leake Gebrargs |
| collection | DOAJ |
| description | Background. Hypotension and bradycardia are the most common complications associated with spinal anesthesia and more common in patients with a history of hypertension. Regular use of antihypertensive medications can prevent these complications. The occurrence of hypotension under spinal anesthesia among controlled hypertensive and normotensive patients with age 40 years and above is still debated. The objective of the study was to compare blood pressure and heart rate changes following spinal anesthesia between controlled hypertensive and normotensive patients undergoing surgery below the umbilicus at Black lion hospital, Addis Ababa, Ethiopia, 2020. Method. A hospital-based prospective cohort study was conducted. A total of 110 elective patients with controlled hypertension (55) and normotensive (55) patients who underwent surgery with spinal anesthesia at black lion hospital during the study period were included. The sample was selected using a systematic random sampling technique. Continuous data of independent and dependent variables were analyzed using an independent sample t-test for normally distributed and Mann–Whitney U-test for nonnormally distributed between the study groups. Categorical variables between the study groups were analyzed using the chi-square test. Descriptive data were displayed using tables and figures. For continuous and categorical variables, a p value <0.05 was considered statistically significant. Results. The incidence of hypotension in the controlled hypertension group (23.6%) was higher than the normotensive group (7.3%) with p value of 0.018. The occurrence of bradycardia was seen to be 12.7% in each group with a p value >0.05. There was a statistically significant difference in the mean systolic blood pressure, mean arterial pressure, mean heart rate, and vasopressor consumption at the measurement time interval between controlled hypertension and normotensive groups. Conclusion. Under spinal anesthesia, patients with controlled hypertension are more likely to develop hypotension than normotensive patients, but on the occurrence of bradycardia, there was no statistically significant difference between the two groups. |
| format | Article |
| id | doaj-art-158f0f2165934041890396651defaf45 |
| institution | Kabale University |
| issn | 1687-6962 1687-6970 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Anesthesiology Research and Practice |
| spelling | doaj-art-158f0f2165934041890396651defaf452025-02-03T01:27:24ZengWileyAnesthesiology Research and Practice1687-69621687-69702021-01-01202110.1155/2021/88912528891252Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Prospective Cohort StudyLeake Gebrargs0Bereket Gebremeskel1Bacha Aberra2Assefa Hika3Yusuf Yimer4Misrak Weldeyohannes5Suleiman Jemal6Degena Behrey7Abere Tilahun8Department of Anesthesiology, College of Health Sciences, Aksum University, Axum, EthiopiaDepartment of Anesthesiology, College of Health Sciences, Aksum University, Axum, EthiopiaDepartment of Anesthesiology, College of Health Sciences, Aksum University, Axum, EthiopiaDepartment of Anesthesiology, College of Health Sciences, Aksum University, Axum, EthiopiaDepartment of Anesthesiology, College of Health Sciences, Aksum University, Axum, EthiopiaDepartment of Anesthesiology, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaDepartment of Anesthesiology, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaDepartment of Adult Health Nursing, College of Health Sciences, Aksum University, Axum, EthiopiaDepartment of Anesthesiology, College of Medicine and Health Sciences, Adigrat University, Adigrat, EthiopiaBackground. Hypotension and bradycardia are the most common complications associated with spinal anesthesia and more common in patients with a history of hypertension. Regular use of antihypertensive medications can prevent these complications. The occurrence of hypotension under spinal anesthesia among controlled hypertensive and normotensive patients with age 40 years and above is still debated. The objective of the study was to compare blood pressure and heart rate changes following spinal anesthesia between controlled hypertensive and normotensive patients undergoing surgery below the umbilicus at Black lion hospital, Addis Ababa, Ethiopia, 2020. Method. A hospital-based prospective cohort study was conducted. A total of 110 elective patients with controlled hypertension (55) and normotensive (55) patients who underwent surgery with spinal anesthesia at black lion hospital during the study period were included. The sample was selected using a systematic random sampling technique. Continuous data of independent and dependent variables were analyzed using an independent sample t-test for normally distributed and Mann–Whitney U-test for nonnormally distributed between the study groups. Categorical variables between the study groups were analyzed using the chi-square test. Descriptive data were displayed using tables and figures. For continuous and categorical variables, a p value <0.05 was considered statistically significant. Results. The incidence of hypotension in the controlled hypertension group (23.6%) was higher than the normotensive group (7.3%) with p value of 0.018. The occurrence of bradycardia was seen to be 12.7% in each group with a p value >0.05. There was a statistically significant difference in the mean systolic blood pressure, mean arterial pressure, mean heart rate, and vasopressor consumption at the measurement time interval between controlled hypertension and normotensive groups. Conclusion. Under spinal anesthesia, patients with controlled hypertension are more likely to develop hypotension than normotensive patients, but on the occurrence of bradycardia, there was no statistically significant difference between the two groups.http://dx.doi.org/10.1155/2021/8891252 |
| spellingShingle | Leake Gebrargs Bereket Gebremeskel Bacha Aberra Assefa Hika Yusuf Yimer Misrak Weldeyohannes Suleiman Jemal Degena Behrey Abere Tilahun Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Prospective Cohort Study Anesthesiology Research and Practice |
| title | Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Prospective Cohort Study |
| title_full | Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Prospective Cohort Study |
| title_fullStr | Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Prospective Cohort Study |
| title_full_unstemmed | Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Prospective Cohort Study |
| title_short | Comparison of Hemodynamic Response following Spinal Anesthesia between Controlled Hypertensive and Normotensive Patients Undergoing Surgery below the Umbilicus: An Observational Prospective Cohort Study |
| title_sort | comparison of hemodynamic response following spinal anesthesia between controlled hypertensive and normotensive patients undergoing surgery below the umbilicus an observational prospective cohort study |
| url | http://dx.doi.org/10.1155/2021/8891252 |
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