The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network

The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network

IntroductionMixed Lineage Kinase Domain-Like Protein (MLKL), as the executor of necroptosis and a critical factor in the inflammation, has been shown to be associated with the progression of hemorrhagic stroke. Studies identified MLKL is a promoting factor in this process, suggesting its potential a...

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Bibliographic Details
Main Authors: Yi Wang, Moran Xu, Xiaoli Zuo, Sheng Wang, Yong Yu, Zhaobing Gao, Jingbo Qie, Ye Jiang, Fang Huang, Bingqing Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mlkl
ICH
hemorrhagic stroke
neuroinflammation
LC-MS/MS
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2024.1509877/full
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