Unraveling Heart Inflammation: Recurrent Myopericarditis Caused by Coxsackie A Virus—A Case Report
ABSTRACT Acute recurrent myopericarditis, characterized by the occurrence of a new myopericarditis event following a symptom‐free interval of 4–6 weeks, is relatively rare lacking definitive guidelines for management. Understanding its prevalence, causes, and optimal management is challenging due to...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-12-01
|
| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.9630 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850105446927433728 |
|---|---|
| author | Maisha Maliha Vikyath Satish Kuan Yu Chi Nishat Shama Sananda Halder Sumaiya Monjur Oishy Amrin Kharawala Dimitrios Varrias Robert T. Fallaice |
| author_facet | Maisha Maliha Vikyath Satish Kuan Yu Chi Nishat Shama Sananda Halder Sumaiya Monjur Oishy Amrin Kharawala Dimitrios Varrias Robert T. Fallaice |
| author_sort | Maisha Maliha |
| collection | DOAJ |
| description | ABSTRACT Acute recurrent myopericarditis, characterized by the occurrence of a new myopericarditis event following a symptom‐free interval of 4–6 weeks, is relatively rare lacking definitive guidelines for management. Understanding its prevalence, causes, and optimal management is challenging due to limited data and insufficient guidelines. This case outlines the diagnostic work‐up and different management modalities for recurrent myopericarditis. A 44‐year‐old African American man with a past medical history of myopericarditis a year ago presented with fever and chest pain for 4 days. The patient was found to have elevated troponin, CRP, and ESR; pericardial effusion along with a Coxsackie A virus titer of 1:800, suggestive of Coxsackie A virus–induced recurrent myopericarditis. The patient responded well to colchicine and a tapering dose of ibuprofen, achieving significant resolution in the pericardial effusion. Recurrent myopericarditis caused by Coxsackie A virus is a relatively rare phenomenon. New onset myopericarditis can be caused by various factors such as infections, autoimmune disorders, neoplasms, metabolic issues, trauma, and drugs, with recurrence rates of 15%–50% in pericarditis patients. Coxsackie A virus is an important and rare etiology of recurrent myopericarditis due to its unique immune evasive traits. The treatment modalities guided by definitive guidelines for recurrent pericarditis can be applied in recurrent myopericarditis with significant resolution of symptoms. Although there are no specific guidelines for managing recurrent myopericarditis, using approaches designed for recurrent pericarditis has shown promising results, and the immune evasive nature of Coxsackie A virus underscores the need for further research to improve our understanding and treatment of this condition. |
| format | Article |
| id | doaj-art-157cde15cd924285b0a28f6fd744f7da |
| institution | OA Journals |
| issn | 2050-0904 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-157cde15cd924285b0a28f6fd744f7da2025-08-20T02:39:04ZengWileyClinical Case Reports2050-09042024-12-011212n/an/a10.1002/ccr3.9630Unraveling Heart Inflammation: Recurrent Myopericarditis Caused by Coxsackie A Virus—A Case ReportMaisha Maliha0Vikyath Satish1Kuan Yu Chi2Nishat Shama3Sananda Halder4Sumaiya Monjur Oishy5Amrin Kharawala6Dimitrios Varrias7Robert T. Fallaice8Dhaka Medical College Dhaka BangladeshJacobi Medical Center New York USAJacobi Medical Center New York USABIRDEM Dhaka BangladeshDhaka Medical College Dhaka BangladeshDhaka Medical College Dhaka BangladeshJacobi Medical Center New York USAJacobi Medical Center New York USAJacobi Medical Center New York USAABSTRACT Acute recurrent myopericarditis, characterized by the occurrence of a new myopericarditis event following a symptom‐free interval of 4–6 weeks, is relatively rare lacking definitive guidelines for management. Understanding its prevalence, causes, and optimal management is challenging due to limited data and insufficient guidelines. This case outlines the diagnostic work‐up and different management modalities for recurrent myopericarditis. A 44‐year‐old African American man with a past medical history of myopericarditis a year ago presented with fever and chest pain for 4 days. The patient was found to have elevated troponin, CRP, and ESR; pericardial effusion along with a Coxsackie A virus titer of 1:800, suggestive of Coxsackie A virus–induced recurrent myopericarditis. The patient responded well to colchicine and a tapering dose of ibuprofen, achieving significant resolution in the pericardial effusion. Recurrent myopericarditis caused by Coxsackie A virus is a relatively rare phenomenon. New onset myopericarditis can be caused by various factors such as infections, autoimmune disorders, neoplasms, metabolic issues, trauma, and drugs, with recurrence rates of 15%–50% in pericarditis patients. Coxsackie A virus is an important and rare etiology of recurrent myopericarditis due to its unique immune evasive traits. The treatment modalities guided by definitive guidelines for recurrent pericarditis can be applied in recurrent myopericarditis with significant resolution of symptoms. Although there are no specific guidelines for managing recurrent myopericarditis, using approaches designed for recurrent pericarditis has shown promising results, and the immune evasive nature of Coxsackie A virus underscores the need for further research to improve our understanding and treatment of this condition.https://doi.org/10.1002/ccr3.9630Coxsackiemyocarditismyopericarditispericarditisrecurrent |
| spellingShingle | Maisha Maliha Vikyath Satish Kuan Yu Chi Nishat Shama Sananda Halder Sumaiya Monjur Oishy Amrin Kharawala Dimitrios Varrias Robert T. Fallaice Unraveling Heart Inflammation: Recurrent Myopericarditis Caused by Coxsackie A Virus—A Case Report Clinical Case Reports Coxsackie myocarditis myopericarditis pericarditis recurrent |
| title | Unraveling Heart Inflammation: Recurrent Myopericarditis Caused by Coxsackie A Virus—A Case Report |
| title_full | Unraveling Heart Inflammation: Recurrent Myopericarditis Caused by Coxsackie A Virus—A Case Report |
| title_fullStr | Unraveling Heart Inflammation: Recurrent Myopericarditis Caused by Coxsackie A Virus—A Case Report |
| title_full_unstemmed | Unraveling Heart Inflammation: Recurrent Myopericarditis Caused by Coxsackie A Virus—A Case Report |
| title_short | Unraveling Heart Inflammation: Recurrent Myopericarditis Caused by Coxsackie A Virus—A Case Report |
| title_sort | unraveling heart inflammation recurrent myopericarditis caused by coxsackie a virus a case report |
| topic | Coxsackie myocarditis myopericarditis pericarditis recurrent |
| url | https://doi.org/10.1002/ccr3.9630 |
| work_keys_str_mv | AT maishamaliha unravelingheartinflammationrecurrentmyopericarditiscausedbycoxsackieavirusacasereport AT vikyathsatish unravelingheartinflammationrecurrentmyopericarditiscausedbycoxsackieavirusacasereport AT kuanyuchi unravelingheartinflammationrecurrentmyopericarditiscausedbycoxsackieavirusacasereport AT nishatshama unravelingheartinflammationrecurrentmyopericarditiscausedbycoxsackieavirusacasereport AT sanandahalder unravelingheartinflammationrecurrentmyopericarditiscausedbycoxsackieavirusacasereport AT sumaiyamonjuroishy unravelingheartinflammationrecurrentmyopericarditiscausedbycoxsackieavirusacasereport AT amrinkharawala unravelingheartinflammationrecurrentmyopericarditiscausedbycoxsackieavirusacasereport AT dimitriosvarrias unravelingheartinflammationrecurrentmyopericarditiscausedbycoxsackieavirusacasereport AT roberttfallaice unravelingheartinflammationrecurrentmyopericarditiscausedbycoxsackieavirusacasereport |