Fentanyl-Induced cerebrocardial syndrome
The clinical case is presented to demonstrate the importance of differential diagnosis of cerebral circulation disorders in patients with acute or chronic toxic effects of psychoactive substances. In the presented observation, a 50-year-old patient was taken to the N.V. Sklifosovsky Research Institu...
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| Format: | Article |
| Language: | Russian |
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Private institution educational organization of higher education "Medical University "ReaViz"
2024-06-01
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| Series: | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
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| Online Access: | https://vestnik.reaviz.ru/jour/article/view/971 |
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| author | L. Kh.-B. Akhmatkhanova E. A. Kovaleva I. S. Aliev Kh. V. Korigova E. V. Shevchenko A. Yu. Simonova G. R. Ramazanov |
| author_facet | L. Kh.-B. Akhmatkhanova E. A. Kovaleva I. S. Aliev Kh. V. Korigova E. V. Shevchenko A. Yu. Simonova G. R. Ramazanov |
| author_sort | L. Kh.-B. Akhmatkhanova |
| collection | DOAJ |
| description | The clinical case is presented to demonstrate the importance of differential diagnosis of cerebral circulation disorders in patients with acute or chronic toxic effects of psychoactive substances. In the presented observation, a 50-year-old patient was taken to the N.V. Sklifosovsky Research Institute of SP with depression of the level of wakefulness to deep deafness, denies the fact of using psychoactive substances when collecting anamnesis, bilateral myosis, diffuse decrease in tone in all extremities. Computed angiotomography of the brain, transcranial dopplerography, magnetic resonance imaging of the brain, electroencephalography were performed – without obvious diagnostic findings. During a detailed examination in a neurological clinic, no data were obtained for a violation of cerebral circulation, a chemical and toxicological examination of urine and blood was performed, fentanyl was detected in biological media. Based on the literature data, however, damage to the nervous system usually occurs due to chronic intoxication and it is not always possible to detect psychoactive substances in biological environments. Due to respiratory depression, the patient was intubated and was on artificial ventilation for 72 hours until spontaneous respiration was restored. After repeated demand, the patient admitted the fact of using fentanyl allegedly to relieve pain, after which he refused further treatment. The conclusion is the need for a chemical and toxicological study of biological media in the case of a violation of consciousness of unclear genesis, however, damage to the nervous system usually occurs due to chronic intoxication and it is not always possible to detect psychoactive substances in biological media. |
| format | Article |
| id | doaj-art-1574877cdda74e92adee3d40ae9a18fa |
| institution | Kabale University |
| issn | 2226-762X 2782-1579 |
| language | Russian |
| publishDate | 2024-06-01 |
| publisher | Private institution educational organization of higher education "Medical University "ReaViz" |
| record_format | Article |
| series | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
| spelling | doaj-art-1574877cdda74e92adee3d40ae9a18fa2025-08-20T03:37:28ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792024-06-01142677210.20340/vmi-rvz.2024.2.CLIN.6602Fentanyl-Induced cerebrocardial syndromeL. Kh.-B. Akhmatkhanova0E. A. Kovaleva1I. S. Aliev2Kh. V. Korigova3E. V. Shevchenko4A. Yu. Simonova5G. R. Ramazanov6N.V. Sklifosovsky Research Institute of Emergency MedicineN.V. Sklifosovsky Research Institute of Emergency MedicineN.V. Sklifosovsky Research Institute of Emergency MedicineN.V. Sklifosovsky Research Institute of Emergency MedicineN.V. Sklifosovsky Research Institute of Emergency MedicineN.V. Sklifosovsky Research Institute of Emergency MedicineN.V. Sklifosovsky Research Institute of Emergency MedicineThe clinical case is presented to demonstrate the importance of differential diagnosis of cerebral circulation disorders in patients with acute or chronic toxic effects of psychoactive substances. In the presented observation, a 50-year-old patient was taken to the N.V. Sklifosovsky Research Institute of SP with depression of the level of wakefulness to deep deafness, denies the fact of using psychoactive substances when collecting anamnesis, bilateral myosis, diffuse decrease in tone in all extremities. Computed angiotomography of the brain, transcranial dopplerography, magnetic resonance imaging of the brain, electroencephalography were performed – without obvious diagnostic findings. During a detailed examination in a neurological clinic, no data were obtained for a violation of cerebral circulation, a chemical and toxicological examination of urine and blood was performed, fentanyl was detected in biological media. Based on the literature data, however, damage to the nervous system usually occurs due to chronic intoxication and it is not always possible to detect psychoactive substances in biological environments. Due to respiratory depression, the patient was intubated and was on artificial ventilation for 72 hours until spontaneous respiration was restored. After repeated demand, the patient admitted the fact of using fentanyl allegedly to relieve pain, after which he refused further treatment. The conclusion is the need for a chemical and toxicological study of biological media in the case of a violation of consciousness of unclear genesis, however, damage to the nervous system usually occurs due to chronic intoxication and it is not always possible to detect psychoactive substances in biological media.https://vestnik.reaviz.ru/jour/article/view/971cerebrocardial syndromeischemic strokefentanylcardiomyopatiya |
| spellingShingle | L. Kh.-B. Akhmatkhanova E. A. Kovaleva I. S. Aliev Kh. V. Korigova E. V. Shevchenko A. Yu. Simonova G. R. Ramazanov Fentanyl-Induced cerebrocardial syndrome Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье cerebrocardial syndrome ischemic stroke fentanyl cardiomyopatiya |
| title | Fentanyl-Induced cerebrocardial syndrome |
| title_full | Fentanyl-Induced cerebrocardial syndrome |
| title_fullStr | Fentanyl-Induced cerebrocardial syndrome |
| title_full_unstemmed | Fentanyl-Induced cerebrocardial syndrome |
| title_short | Fentanyl-Induced cerebrocardial syndrome |
| title_sort | fentanyl induced cerebrocardial syndrome |
| topic | cerebrocardial syndrome ischemic stroke fentanyl cardiomyopatiya |
| url | https://vestnik.reaviz.ru/jour/article/view/971 |
| work_keys_str_mv | AT lkhbakhmatkhanova fentanylinducedcerebrocardialsyndrome AT eakovaleva fentanylinducedcerebrocardialsyndrome AT isaliev fentanylinducedcerebrocardialsyndrome AT khvkorigova fentanylinducedcerebrocardialsyndrome AT evshevchenko fentanylinducedcerebrocardialsyndrome AT ayusimonova fentanylinducedcerebrocardialsyndrome AT grramazanov fentanylinducedcerebrocardialsyndrome |