Proportional constrained longitudinal data analysis models for clinical trials in sporadic Alzheimer's disease
Abstract Introduction Clinical trials for sporadic Alzheimer's disease generally use mixed models for repeated measures (MMRM) or, to a lesser degree, constrained longitudinal data analysis models (cLDA) as the analysis model with time since baseline as a categorical variable. Inferences using...
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| Main Authors: | Guoqiao Wang, Lei Liu, Yan Li, Andrew J. Aschenbrenner, Randall J. Bateman, Paul Delmar, Lon S. Schneider, Richard E. Kennedy, Gary R. Cutter, Chengjie Xiong |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
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| Series: | Alzheimer’s & Dementia: Translational Research & Clinical Interventions |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/trc2.12286 |
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