Lung Injury Prediction Score Is Useful in Predicting Acute Respiratory Distress Syndrome and Mortality in Surgical Critical Care Patients
Background. Lung injury prediction score (LIPS) is valuable for early recognition of ventilated patients at high risk for developing acute respiratory distress syndrome (ARDS). This study analyzes the value of LIPS in predicting ARDS and mortality among ventilated surgical patients. Methods. IRB app...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Critical Care Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2015/157408 |
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| author | Zachary M. Bauman Marika Y. Gassner Megan A. Coughlin Meredith Mahan Jill Watras |
| author_facet | Zachary M. Bauman Marika Y. Gassner Megan A. Coughlin Meredith Mahan Jill Watras |
| author_sort | Zachary M. Bauman |
| collection | DOAJ |
| description | Background. Lung injury prediction score (LIPS) is valuable for early recognition of ventilated patients at high risk for developing acute respiratory distress syndrome (ARDS). This study analyzes the value of LIPS in predicting ARDS and mortality among ventilated surgical patients. Methods. IRB approved, prospective observational study including all ventilated patients admitted to the surgical intensive care unit at a single tertiary center over 6 months. ARDS was defined using the Berlin criteria. LIPS were calculated for all patients and analyzed. Logistic regression models evaluated the ability of LIPS to predict development of ARDS and mortality. A receiver operator characteristic (ROC) curve demonstrated the optimal LIPS value to statistically predict development of ARDS. Results. 268 ventilated patients were observed; 141 developed ARDS and 127 did not. The average LIPS for patients who developed ARDS was 8.8±2.8 versus 5.4±2.8 for those who did not (p<0.001). An ROC area under the curve of 0.79 demonstrates LIPS is statistically powerful for predicting ARDS development. Furthermore, for every 1-unit increase in LIPS, the odds of developing ARDS increase by 1.50 (p<0.001) and odds of ICU mortality increase by 1.22 (p<0.001). Conclusion. LIPS is reliable for predicting development of ARDS and predicting mortality in critically ill surgical patients. |
| format | Article |
| id | doaj-art-15690f4b0b3b44228c3e4e9d6d3adc97 |
| institution | OA Journals |
| issn | 2090-1305 2090-1313 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
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| series | Critical Care Research and Practice |
| spelling | doaj-art-15690f4b0b3b44228c3e4e9d6d3adc972025-08-20T02:02:40ZengWileyCritical Care Research and Practice2090-13052090-13132015-01-01201510.1155/2015/157408157408Lung Injury Prediction Score Is Useful in Predicting Acute Respiratory Distress Syndrome and Mortality in Surgical Critical Care PatientsZachary M. Bauman0Marika Y. Gassner1Megan A. Coughlin2Meredith Mahan3Jill Watras4Henry Ford Hospital, Detroit, MI 48202, USAHenry Ford Hospital, Detroit, MI 48202, USAHenry Ford Hospital, Detroit, MI 48202, USAHenry Ford Hospital, Detroit, MI 48202, USAHenry Ford Hospital, Detroit, MI 48202, USABackground. Lung injury prediction score (LIPS) is valuable for early recognition of ventilated patients at high risk for developing acute respiratory distress syndrome (ARDS). This study analyzes the value of LIPS in predicting ARDS and mortality among ventilated surgical patients. Methods. IRB approved, prospective observational study including all ventilated patients admitted to the surgical intensive care unit at a single tertiary center over 6 months. ARDS was defined using the Berlin criteria. LIPS were calculated for all patients and analyzed. Logistic regression models evaluated the ability of LIPS to predict development of ARDS and mortality. A receiver operator characteristic (ROC) curve demonstrated the optimal LIPS value to statistically predict development of ARDS. Results. 268 ventilated patients were observed; 141 developed ARDS and 127 did not. The average LIPS for patients who developed ARDS was 8.8±2.8 versus 5.4±2.8 for those who did not (p<0.001). An ROC area under the curve of 0.79 demonstrates LIPS is statistically powerful for predicting ARDS development. Furthermore, for every 1-unit increase in LIPS, the odds of developing ARDS increase by 1.50 (p<0.001) and odds of ICU mortality increase by 1.22 (p<0.001). Conclusion. LIPS is reliable for predicting development of ARDS and predicting mortality in critically ill surgical patients.http://dx.doi.org/10.1155/2015/157408 |
| spellingShingle | Zachary M. Bauman Marika Y. Gassner Megan A. Coughlin Meredith Mahan Jill Watras Lung Injury Prediction Score Is Useful in Predicting Acute Respiratory Distress Syndrome and Mortality in Surgical Critical Care Patients Critical Care Research and Practice |
| title | Lung Injury Prediction Score Is Useful in Predicting Acute Respiratory Distress Syndrome and Mortality in Surgical Critical Care Patients |
| title_full | Lung Injury Prediction Score Is Useful in Predicting Acute Respiratory Distress Syndrome and Mortality in Surgical Critical Care Patients |
| title_fullStr | Lung Injury Prediction Score Is Useful in Predicting Acute Respiratory Distress Syndrome and Mortality in Surgical Critical Care Patients |
| title_full_unstemmed | Lung Injury Prediction Score Is Useful in Predicting Acute Respiratory Distress Syndrome and Mortality in Surgical Critical Care Patients |
| title_short | Lung Injury Prediction Score Is Useful in Predicting Acute Respiratory Distress Syndrome and Mortality in Surgical Critical Care Patients |
| title_sort | lung injury prediction score is useful in predicting acute respiratory distress syndrome and mortality in surgical critical care patients |
| url | http://dx.doi.org/10.1155/2015/157408 |
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