Evidence that bank vole PrP is a universal acceptor for prions.

Evidence that bank vole PrP is a universal acceptor for prions.

Bank voles are uniquely susceptible to a wide range of prion strains isolated from many different species. To determine if this enhanced susceptibility to interspecies prion transmission is encoded within the sequence of the bank vole prion protein (BVPrP), we inoculated Tg(M109) and Tg(I109) mice,...

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Bibliographic Details
Main Authors: Joel C Watts, Kurt Giles, Smita Patel, Abby Oehler, Stephen J DeArmond, Stanley B Prusiner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1003990&type=printable
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