Potential of mir-299-5p to modulate LPS-induced inflammation and osteogenic differentiation of periodontal stem cells by targeting PUM2

Potential of mir-299-5p to modulate LPS-induced inflammation and osteogenic differentiation of periodontal stem cells by targeting PUM2

Abstract Background Periodontitis is a prevalent oral disease that significantly impacts human quality of life. This study aimed at the influence of microRNA-299-5p (miR-299-5p) on regulating lipopolysaccharide (LPS)-induced osteogenic differentiation of periodontal ligament stem cells (PDLSCs). Met...

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Bibliographic Details
Main Authors: Qing-Hua Zhang, Yu-Xi Zhang, Ling Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Oral Health
Subjects:
Chronic periodontitis
PDLSCs
Inflammatory
Differentiation
imiR-299-5p
PUM2
Online Access:https://doi.org/10.1186/s12903-025-05617-y
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