Enhancing diagnostic innovation by leveraging the co-creation approach

Digital innovation in precision diagnostics requires addressing complex challenges, such as implementation, adoption, equity, and sustainability. This study introduces a co-creation framework that leverages the pre-competitive space to drive collaborative innovation in personalized diagnostics. Over...

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Main Authors: Jochen K. Lennerz, Alexandra Farfsing, Tim-Rasmus Kiehl, Sven Perner, Joost van Duuren, Marleen Christ, Jan W. Farfsing
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Pathology Informatics
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S215335392500046X
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author Jochen K. Lennerz
Alexandra Farfsing
Tim-Rasmus Kiehl
Sven Perner
Joost van Duuren
Marleen Christ
Jan W. Farfsing
author_facet Jochen K. Lennerz
Alexandra Farfsing
Tim-Rasmus Kiehl
Sven Perner
Joost van Duuren
Marleen Christ
Jan W. Farfsing
author_sort Jochen K. Lennerz
collection DOAJ
description Digital innovation in precision diagnostics requires addressing complex challenges, such as implementation, adoption, equity, and sustainability. This study introduces a co-creation framework that leverages the pre-competitive space to drive collaborative innovation in personalized diagnostics. Over 5 years, a multidisciplinary community of stakeholders from computational pathology, oncology, genetics, digital medicine, and industry engaged in design-thinking workshops to identify unmet medical needs and co-develop solutions. These efforts led to 15 pilot projects, with 7 successfully implemented, including an automated lab system enhancing workflow efficiency. The co-creation approach fostered strategic alignment, community building, and integration of diverse perspectives, resulting in tangible outputs (datasets, publications, and resources) and intangible benefits (networking, market insight). This framework demonstrates how collaborative ecosystems accelerate diagnostic innovations and offer a scalable model for advancing personalized healthcare. Co-creation addresses interdisciplinary silos, promotes patient-centered solutions, and adapts to evolving regulatory landscapes, making it a catalyst for impactful healthcare transformation.
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language English
publishDate 2025-08-01
publisher Elsevier
record_format Article
series Journal of Pathology Informatics
spelling doaj-art-1550b91599e84705bde46cfc1fcc896e2025-08-20T03:50:22ZengElsevierJournal of Pathology Informatics2153-35392025-08-011810046010.1016/j.jpi.2025.100460Enhancing diagnostic innovation by leveraging the co-creation approachJochen K. Lennerz0Alexandra Farfsing1Tim-Rasmus Kiehl2Sven Perner3Joost van Duuren4Marleen Christ5Jan W. Farfsing6Boston Gene, Waltham, MA, USARoche Diagnostics Deutschland GmbH, Mannheim, Germany; Corresponding author at: Roche Diagnostics Deutschland GmbH, Sandhofer Strasse 116, 68305 Mannheim, Germany.Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Informatics, Berlin, GermanyPATHORA Institut für Pathologie und Gewebemedizin, Gerhard-Kindler-Str., 1772770 Reutlingen, GermanyRoche Diagnostics Deutschland GmbH, Mannheim, GermanyRoche Diagnostics Deutschland GmbH, Mannheim, GermanyRoche Diagnostics Deutschland GmbH, Mannheim, GermanyDigital innovation in precision diagnostics requires addressing complex challenges, such as implementation, adoption, equity, and sustainability. This study introduces a co-creation framework that leverages the pre-competitive space to drive collaborative innovation in personalized diagnostics. Over 5 years, a multidisciplinary community of stakeholders from computational pathology, oncology, genetics, digital medicine, and industry engaged in design-thinking workshops to identify unmet medical needs and co-develop solutions. These efforts led to 15 pilot projects, with 7 successfully implemented, including an automated lab system enhancing workflow efficiency. The co-creation approach fostered strategic alignment, community building, and integration of diverse perspectives, resulting in tangible outputs (datasets, publications, and resources) and intangible benefits (networking, market insight). This framework demonstrates how collaborative ecosystems accelerate diagnostic innovations and offer a scalable model for advancing personalized healthcare. Co-creation addresses interdisciplinary silos, promotes patient-centered solutions, and adapts to evolving regulatory landscapes, making it a catalyst for impactful healthcare transformation.http://www.sciencedirect.com/science/article/pii/S215335392500046XCo-creationCo-innovationPre-competitive spaceDigitizationBiomarkersAutomation
spellingShingle Jochen K. Lennerz
Alexandra Farfsing
Tim-Rasmus Kiehl
Sven Perner
Joost van Duuren
Marleen Christ
Jan W. Farfsing
Enhancing diagnostic innovation by leveraging the co-creation approach
Journal of Pathology Informatics
Co-creation
Co-innovation
Pre-competitive space
Digitization
Biomarkers
Automation
title Enhancing diagnostic innovation by leveraging the co-creation approach
title_full Enhancing diagnostic innovation by leveraging the co-creation approach
title_fullStr Enhancing diagnostic innovation by leveraging the co-creation approach
title_full_unstemmed Enhancing diagnostic innovation by leveraging the co-creation approach
title_short Enhancing diagnostic innovation by leveraging the co-creation approach
title_sort enhancing diagnostic innovation by leveraging the co creation approach
topic Co-creation
Co-innovation
Pre-competitive space
Digitization
Biomarkers
Automation
url http://www.sciencedirect.com/science/article/pii/S215335392500046X
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