An Autopsy Case of Fulminant Amebic Colitis in a Patient with a History of Rheumatoid Arthritis

Generally, amebic colitis is localized around the mucosal membrane and often accompanied by diarrhea and abdominal pain. We describe a patient with a history of rheumatoid arthritis who had received prolonged steroid therapy. The patient complained of breathing difficulties because of rheumatoid lun...

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Main Authors: Naoko Kawabe, Fuyuki Sato, Miho Nagasawa, Masako Nakanishi, Yasuteru Muragaki
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2016/8470867
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author Naoko Kawabe
Fuyuki Sato
Miho Nagasawa
Masako Nakanishi
Yasuteru Muragaki
author_facet Naoko Kawabe
Fuyuki Sato
Miho Nagasawa
Masako Nakanishi
Yasuteru Muragaki
author_sort Naoko Kawabe
collection DOAJ
description Generally, amebic colitis is localized around the mucosal membrane and often accompanied by diarrhea and abdominal pain. We describe a patient with a history of rheumatoid arthritis who had received prolonged steroid therapy. The patient complained of breathing difficulties because of rheumatoid lung disease. Although the patient was given antibacterial agent, the symptoms did not improve until death. We did an autopsy and found that he had fulminant amebic colitis, although the patient was not previously examined. Histochemical analysis revealed severe inflammation and full-thickness necrosis of the colon by ameba, suggesting the involvement of ameba in the progression of the overall condition.
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spelling doaj-art-154ece4e04a54fb783cb5fb6044151362025-08-20T02:02:01ZengWileyCase Reports in Rheumatology2090-68892090-68972016-01-01201610.1155/2016/84708678470867An Autopsy Case of Fulminant Amebic Colitis in a Patient with a History of Rheumatoid ArthritisNaoko Kawabe0Fuyuki Sato1Miho Nagasawa2Masako Nakanishi3Yasuteru Muragaki4Department of Pathology, Wakayama Medical University School of Medicine, Wakayama 641-8509, JapanDepartment of Pathology, Wakayama Medical University School of Medicine, Wakayama 641-8509, JapanDepartment of Pathology, Wakayama Medical University School of Medicine, Wakayama 641-8509, JapanDepartment of Pathology, Wakayama Medical University School of Medicine, Wakayama 641-8509, JapanDepartment of Pathology, Wakayama Medical University School of Medicine, Wakayama 641-8509, JapanGenerally, amebic colitis is localized around the mucosal membrane and often accompanied by diarrhea and abdominal pain. We describe a patient with a history of rheumatoid arthritis who had received prolonged steroid therapy. The patient complained of breathing difficulties because of rheumatoid lung disease. Although the patient was given antibacterial agent, the symptoms did not improve until death. We did an autopsy and found that he had fulminant amebic colitis, although the patient was not previously examined. Histochemical analysis revealed severe inflammation and full-thickness necrosis of the colon by ameba, suggesting the involvement of ameba in the progression of the overall condition.http://dx.doi.org/10.1155/2016/8470867
spellingShingle Naoko Kawabe
Fuyuki Sato
Miho Nagasawa
Masako Nakanishi
Yasuteru Muragaki
An Autopsy Case of Fulminant Amebic Colitis in a Patient with a History of Rheumatoid Arthritis
Case Reports in Rheumatology
title An Autopsy Case of Fulminant Amebic Colitis in a Patient with a History of Rheumatoid Arthritis
title_full An Autopsy Case of Fulminant Amebic Colitis in a Patient with a History of Rheumatoid Arthritis
title_fullStr An Autopsy Case of Fulminant Amebic Colitis in a Patient with a History of Rheumatoid Arthritis
title_full_unstemmed An Autopsy Case of Fulminant Amebic Colitis in a Patient with a History of Rheumatoid Arthritis
title_short An Autopsy Case of Fulminant Amebic Colitis in a Patient with a History of Rheumatoid Arthritis
title_sort autopsy case of fulminant amebic colitis in a patient with a history of rheumatoid arthritis
url http://dx.doi.org/10.1155/2016/8470867
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