A Rare Case of a Pregnant Woman with Severe Thrombocytopenia Associated with Systemic Lupus Erythematosus
This case report describes a 22-year-old pregnant woman with systemic lupus erythematosus (SLE) and severe thrombocytopenia at 32 weeks of gestation with dichorionic diamniotic (DCDA) twins. She had a platelet count of 3,000/μL, persistent thrombocytopenia despite transfusions, and symptoms includin...
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Prathima Institute of Medical Sciences
2024-12-01
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| Series: | Perspectives In Medical Research |
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| Online Access: | https://www.pimr.org.in/2024-vol12-issue-3/1047799pimr120312-2024.pdf |
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| author | Gitanshi Arora Gauri Abhishek Prabhu |
| author_facet | Gitanshi Arora Gauri Abhishek Prabhu |
| author_sort | Gitanshi Arora |
| collection | DOAJ |
| description | This case report describes a 22-year-old pregnant woman with systemic lupus erythematosus (SLE) and severe thrombocytopenia at 32 weeks of gestation with dichorionic diamniotic (DCDA) twins. She had a platelet count of 3,000/μL, persistent thrombocytopenia despite transfusions, and symptoms including rashes and muscle cramps. Diagnosis was confirmed with a positive antinuclear antibody (ANA) test. Treatment included methylprednisolone pulse therapy, hydroxychloroquine, and intravenous immunoglobulin (IVIG).
At 34 weeks and 4 days, the patient went into preterm labor and underwent a cesarean section. Preoperative platelet transfusions raised her platelet count to 51,000/μL. Both twins were delivered safely and admitted to the NICU for prematurity. Postoperative care included immunosuppressive therapy, antihypertensives, and antibiotics, with steady improvement in the patient’s condition and platelet count.
This case highlights the challenges of managing SLE with severe thrombocytopenia during pregnancy, especially with twins. Early diagnosis, tailored treatment, and coordinated multidisciplinary care led to positive maternal and neonatal outcomes. This emphasizes the importance of proactive management in high-risk pregnancies to ensure the best possible results. |
| format | Article |
| id | doaj-art-154219ba2388479595922bc263a95b82 |
| institution | Kabale University |
| issn | 2348-1447 2348-229X |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Prathima Institute of Medical Sciences |
| record_format | Article |
| series | Perspectives In Medical Research |
| spelling | doaj-art-154219ba2388479595922bc263a95b822025-01-06T07:10:04ZengPrathima Institute of Medical SciencesPerspectives In Medical Research2348-14472348-229X2024-12-01123666810.47799/pimr.1203.1212A Rare Case of a Pregnant Woman with Severe Thrombocytopenia Associated with Systemic Lupus ErythematosusGitanshi Arora0Gauri Abhishek Prabhu1Junior Resident, Dept Of Obstetrics and Gynecology, KAHER’s Jawaharlal Nehru Medical College, Belagavi, KarnatakaAssistant Professor, Department of Obstetrics and Gynaecology, KAHER’s Jawaharlal Nehru Medical College, Belagavi, KarnatakaThis case report describes a 22-year-old pregnant woman with systemic lupus erythematosus (SLE) and severe thrombocytopenia at 32 weeks of gestation with dichorionic diamniotic (DCDA) twins. She had a platelet count of 3,000/μL, persistent thrombocytopenia despite transfusions, and symptoms including rashes and muscle cramps. Diagnosis was confirmed with a positive antinuclear antibody (ANA) test. Treatment included methylprednisolone pulse therapy, hydroxychloroquine, and intravenous immunoglobulin (IVIG). At 34 weeks and 4 days, the patient went into preterm labor and underwent a cesarean section. Preoperative platelet transfusions raised her platelet count to 51,000/μL. Both twins were delivered safely and admitted to the NICU for prematurity. Postoperative care included immunosuppressive therapy, antihypertensives, and antibiotics, with steady improvement in the patient’s condition and platelet count. This case highlights the challenges of managing SLE with severe thrombocytopenia during pregnancy, especially with twins. Early diagnosis, tailored treatment, and coordinated multidisciplinary care led to positive maternal and neonatal outcomes. This emphasizes the importance of proactive management in high-risk pregnancies to ensure the best possible results.https://www.pimr.org.in/2024-vol12-issue-3/1047799pimr120312-2024.pdfsystemic lupus erythematosuspregnancy complicationslupus flareshigh-risk pregnancymaternal and neonatal outcomes |
| spellingShingle | Gitanshi Arora Gauri Abhishek Prabhu A Rare Case of a Pregnant Woman with Severe Thrombocytopenia Associated with Systemic Lupus Erythematosus Perspectives In Medical Research systemic lupus erythematosus pregnancy complications lupus flares high-risk pregnancy maternal and neonatal outcomes |
| title | A Rare Case of a Pregnant Woman with Severe Thrombocytopenia Associated with Systemic Lupus Erythematosus |
| title_full | A Rare Case of a Pregnant Woman with Severe Thrombocytopenia Associated with Systemic Lupus Erythematosus |
| title_fullStr | A Rare Case of a Pregnant Woman with Severe Thrombocytopenia Associated with Systemic Lupus Erythematosus |
| title_full_unstemmed | A Rare Case of a Pregnant Woman with Severe Thrombocytopenia Associated with Systemic Lupus Erythematosus |
| title_short | A Rare Case of a Pregnant Woman with Severe Thrombocytopenia Associated with Systemic Lupus Erythematosus |
| title_sort | rare case of a pregnant woman with severe thrombocytopenia associated with systemic lupus erythematosus |
| topic | systemic lupus erythematosus pregnancy complications lupus flares high-risk pregnancy maternal and neonatal outcomes |
| url | https://www.pimr.org.in/2024-vol12-issue-3/1047799pimr120312-2024.pdf |
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