Efficacy and Safety of Recombinant Human Prourokinase in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis

Acute ischemic stroke (AIS) is a leading cause of mortality and disability worldwide. Recombinant human prourokinase (rhPro-UK) has emerged as a promising thrombolytic agent amid the global shortage of thrombolytics. We assessed the safety and efficacy of rhPro-UK in AIS patients within 4.5 h of str...

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Main Authors: Abdulaziz A. Alzahrani MBBCh, Ahmed A. Maiz MBBCh, Ahmed A. Ibrahim MBBCh, Mohamed Rifai MBBCh, Suhaiyh Sanad Alotibi MBBCh, Leena Salem MBBCh, Hadeel A. Alzabidi MBBCh, Sarah Mansour Alshehri MBBCh, Yara Fahad Almazyad MBBCh, Zeyad T. Mansour MBBCh, Abubaker Osman Ahmed MD
Format: Article
Language:English
Published: SAGE Publishing 2025-04-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296251328025
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