Photodynamic Therapy with Protoporphyrin IX Precursors Using Artificial Daylight Improves Skin Antisepsis for Orthopedic Surgeries

Photodynamic Therapy with Protoporphyrin IX Precursors Using Artificial Daylight Improves Skin Antisepsis for Orthopedic Surgeries

Classical preoperative skin antisepsis is insufficient in completely eliminating bacterial skin colonization for arthroplasty. In contrast, photodynamic therapy (PDT) with red light and methyl-aminolevulinate (MAL), combined with skin antisepsis, led to the absence of bacterial growth in healthy par...

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Bibliographic Details
Main Authors: Tiziano A. Schweizer, Julia S. Würmli, Julia Prinz, Maximilian Wölfle, Roger Marti, Hendrik Koliwer-Brandl, Ashley M. Rooney, Vanni Benvenga, Adrian Egli, Laurence Imhof, Philipp P. Bosshard, Yvonne Achermann
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Microorganisms
Subjects:
skin antisepsis
photodynamic therapy (PDT)
daylight
5-aminolevulinic acid
methyl-aminolevulinate
bacteria
Online Access:https://www.mdpi.com/2076-2607/13/1/204
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