Update on Intra-Arterial Chemotherapy for Retinoblastoma
The tools for managing retinoblastoma have been increasing in the past decade. While globe-salvage still relies heavily on intravenous chemotherapy, tumors in advanced stage that failed chemotherapy are now referred for intra-arterial chemotherapy (IAC) to avoid enucleation. However, IAC still has m...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/869604 |
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| author | Mario Zanaty Guilherme Barros Nohra Chalouhi Robert M. Starke Philip Manasseh Stavropoula I. Tjoumakaris Carol L. Shields David Hasan Ketan Bulsara Robert H. Rosenwasser Pascal Jabbour |
| author_facet | Mario Zanaty Guilherme Barros Nohra Chalouhi Robert M. Starke Philip Manasseh Stavropoula I. Tjoumakaris Carol L. Shields David Hasan Ketan Bulsara Robert H. Rosenwasser Pascal Jabbour |
| author_sort | Mario Zanaty |
| collection | DOAJ |
| description | The tools for managing retinoblastoma have been increasing in the past decade. While globe-salvage still relies heavily on intravenous chemotherapy, tumors in advanced stage that failed chemotherapy are now referred for intra-arterial chemotherapy (IAC) to avoid enucleation. However, IAC still has many obstacles to overcome. We present an update on the indications, complications, limitations, success, and technical aspects of IAC. Given its safety and high efficacy, it is expected that IAC will replace conventional strategies and will become a first-line option even for tumors that are amenable for other strategies. |
| format | Article |
| id | doaj-art-15278e724b034804bf6d66544dbea8d5 |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-15278e724b034804bf6d66544dbea8d52025-08-20T03:54:29ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/869604869604Update on Intra-Arterial Chemotherapy for RetinoblastomaMario Zanaty0Guilherme Barros1Nohra Chalouhi2Robert M. Starke3Philip Manasseh4Stavropoula I. Tjoumakaris5Carol L. Shields6David Hasan7Ketan Bulsara8Robert H. Rosenwasser9Pascal Jabbour10Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurosurgery, University of Virginia, Charlottesville, VA 22908, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Ophthalmology, Thomas Jefferson University Hospital, Philadelphia, PA 19017, USADepartment of Neurosurgery, University of Iowa School of Medicine, Iowa City, IA 52242, USADepartment of Neurosurgery, Yale University School of Medicine, New Haven, CT 06510, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USADepartment of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, PA 19107, USAThe tools for managing retinoblastoma have been increasing in the past decade. While globe-salvage still relies heavily on intravenous chemotherapy, tumors in advanced stage that failed chemotherapy are now referred for intra-arterial chemotherapy (IAC) to avoid enucleation. However, IAC still has many obstacles to overcome. We present an update on the indications, complications, limitations, success, and technical aspects of IAC. Given its safety and high efficacy, it is expected that IAC will replace conventional strategies and will become a first-line option even for tumors that are amenable for other strategies.http://dx.doi.org/10.1155/2014/869604 |
| spellingShingle | Mario Zanaty Guilherme Barros Nohra Chalouhi Robert M. Starke Philip Manasseh Stavropoula I. Tjoumakaris Carol L. Shields David Hasan Ketan Bulsara Robert H. Rosenwasser Pascal Jabbour Update on Intra-Arterial Chemotherapy for Retinoblastoma The Scientific World Journal |
| title | Update on Intra-Arterial Chemotherapy for Retinoblastoma |
| title_full | Update on Intra-Arterial Chemotherapy for Retinoblastoma |
| title_fullStr | Update on Intra-Arterial Chemotherapy for Retinoblastoma |
| title_full_unstemmed | Update on Intra-Arterial Chemotherapy for Retinoblastoma |
| title_short | Update on Intra-Arterial Chemotherapy for Retinoblastoma |
| title_sort | update on intra arterial chemotherapy for retinoblastoma |
| url | http://dx.doi.org/10.1155/2014/869604 |
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