Update on Intra-Arterial Chemotherapy for Retinoblastoma

The tools for managing retinoblastoma have been increasing in the past decade. While globe-salvage still relies heavily on intravenous chemotherapy, tumors in advanced stage that failed chemotherapy are now referred for intra-arterial chemotherapy (IAC) to avoid enucleation. However, IAC still has m...

Full description

Saved in:
Bibliographic Details
Main Authors: Mario Zanaty, Guilherme Barros, Nohra Chalouhi, Robert M. Starke, Philip Manasseh, Stavropoula I. Tjoumakaris, Carol L. Shields, David Hasan, Ketan Bulsara, Robert H. Rosenwasser, Pascal Jabbour
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2014/869604
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The tools for managing retinoblastoma have been increasing in the past decade. While globe-salvage still relies heavily on intravenous chemotherapy, tumors in advanced stage that failed chemotherapy are now referred for intra-arterial chemotherapy (IAC) to avoid enucleation. However, IAC still has many obstacles to overcome. We present an update on the indications, complications, limitations, success, and technical aspects of IAC. Given its safety and high efficacy, it is expected that IAC will replace conventional strategies and will become a first-line option even for tumors that are amenable for other strategies.
ISSN:2356-6140
1537-744X