Progress in Research on Metal Ion Crosslinking Alginate-Based Gels
Alginate is an important natural biopolymer and metal ion-induced gelation is one of its most significant functional properties. Alginate-based hydrogels crosslinked with metal ions are commonly utilized in the food, biomedical, tissue engineering, and environment fields. The process of metal ion-in...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-12-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/11/1/16 |
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| author | Yantao Wang Zhenpeng Shen Huili Wang Zhaoping Song Dehai Yu Guodong Li Xiaona Liu Wenxia Liu |
| author_facet | Yantao Wang Zhenpeng Shen Huili Wang Zhaoping Song Dehai Yu Guodong Li Xiaona Liu Wenxia Liu |
| author_sort | Yantao Wang |
| collection | DOAJ |
| description | Alginate is an important natural biopolymer and metal ion-induced gelation is one of its most significant functional properties. Alginate-based hydrogels crosslinked with metal ions are commonly utilized in the food, biomedical, tissue engineering, and environment fields. The process of metal ion-induced alginate gelation has been the subject of thorough research over the last few decades. This review aims to summarize the mechanisms of alginate hydrogels induced by different cations (primarily including Ca<sup>2+</sup>, Ba<sup>2+</sup>, Cu<sup>2+</sup>, Sr<sup>2+</sup>, Fe<sup>2+</sup>/Fe<sup>3+</sup>, and Al<sup>3+</sup>). Metal ion-induced alginate gelation shows different preferences for α-L-guluronic acid (G), β-D-mannuronic acid (M), and GM blocks. Some metal ions can also selectively bind to the carboxyl groups of guluronic acid. The properties and applications of these alginate-based hydrogels are also discussed. The primary objective of this review is to provide useful information for exploring the practical applications of alginate. |
| format | Article |
| id | doaj-art-1509f457fab540388f45ab907ccd8b2f |
| institution | Kabale University |
| issn | 2310-2861 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj-art-1509f457fab540388f45ab907ccd8b2f2025-01-24T13:33:46ZengMDPI AGGels2310-28612024-12-011111610.3390/gels11010016Progress in Research on Metal Ion Crosslinking Alginate-Based GelsYantao Wang0Zhenpeng Shen1Huili Wang2Zhaoping Song3Dehai Yu4Guodong Li5Xiaona Liu6Wenxia Liu7State Key Laboratory of Biobased Materials and Green Papermaking, Qilu University of Technology, Jinan 250353, ChinaState Key Laboratory of Biobased Materials and Green Papermaking, Qilu University of Technology, Jinan 250353, ChinaState Key Laboratory of Biobased Materials and Green Papermaking, Qilu University of Technology, Jinan 250353, ChinaState Key Laboratory of Biobased Materials and Green Papermaking, Qilu University of Technology, Jinan 250353, ChinaState Key Laboratory of Biobased Materials and Green Papermaking, Qilu University of Technology, Jinan 250353, ChinaState Key Laboratory of Biobased Materials and Green Papermaking, Qilu University of Technology, Jinan 250353, ChinaState Key Laboratory of Biobased Materials and Green Papermaking, Qilu University of Technology, Jinan 250353, ChinaState Key Laboratory of Biobased Materials and Green Papermaking, Qilu University of Technology, Jinan 250353, ChinaAlginate is an important natural biopolymer and metal ion-induced gelation is one of its most significant functional properties. Alginate-based hydrogels crosslinked with metal ions are commonly utilized in the food, biomedical, tissue engineering, and environment fields. The process of metal ion-induced alginate gelation has been the subject of thorough research over the last few decades. This review aims to summarize the mechanisms of alginate hydrogels induced by different cations (primarily including Ca<sup>2+</sup>, Ba<sup>2+</sup>, Cu<sup>2+</sup>, Sr<sup>2+</sup>, Fe<sup>2+</sup>/Fe<sup>3+</sup>, and Al<sup>3+</sup>). Metal ion-induced alginate gelation shows different preferences for α-L-guluronic acid (G), β-D-mannuronic acid (M), and GM blocks. Some metal ions can also selectively bind to the carboxyl groups of guluronic acid. The properties and applications of these alginate-based hydrogels are also discussed. The primary objective of this review is to provide useful information for exploring the practical applications of alginate.https://www.mdpi.com/2310-2861/11/1/16metal ionalginategelapplication |
| spellingShingle | Yantao Wang Zhenpeng Shen Huili Wang Zhaoping Song Dehai Yu Guodong Li Xiaona Liu Wenxia Liu Progress in Research on Metal Ion Crosslinking Alginate-Based Gels Gels metal ion alginate gel application |
| title | Progress in Research on Metal Ion Crosslinking Alginate-Based Gels |
| title_full | Progress in Research on Metal Ion Crosslinking Alginate-Based Gels |
| title_fullStr | Progress in Research on Metal Ion Crosslinking Alginate-Based Gels |
| title_full_unstemmed | Progress in Research on Metal Ion Crosslinking Alginate-Based Gels |
| title_short | Progress in Research on Metal Ion Crosslinking Alginate-Based Gels |
| title_sort | progress in research on metal ion crosslinking alginate based gels |
| topic | metal ion alginate gel application |
| url | https://www.mdpi.com/2310-2861/11/1/16 |
| work_keys_str_mv | AT yantaowang progressinresearchonmetalioncrosslinkingalginatebasedgels AT zhenpengshen progressinresearchonmetalioncrosslinkingalginatebasedgels AT huiliwang progressinresearchonmetalioncrosslinkingalginatebasedgels AT zhaopingsong progressinresearchonmetalioncrosslinkingalginatebasedgels AT dehaiyu progressinresearchonmetalioncrosslinkingalginatebasedgels AT guodongli progressinresearchonmetalioncrosslinkingalginatebasedgels AT xiaonaliu progressinresearchonmetalioncrosslinkingalginatebasedgels AT wenxialiu progressinresearchonmetalioncrosslinkingalginatebasedgels |