Compression force promotes the osteogenic differentiation of periodontal ligament stem cells by regulating NAT10-mediated ac4C modification of BMP2

Compression force promotes the osteogenic differentiation of periodontal ligament stem cells by regulating NAT10-mediated ac4C modification of BMP2

Abstract Background Orthodontic treatment applies specific corrective forces to teeth, transmitting stress to periodontal tissue, thereby regulating the growth and development of periodontal ligament stem cells (PDLSCs). Recently, N-acetyltransferase 10 (NAT10) mediated N4-acetylcytidine (ac4C) modi...

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Bibliographic Details
Main Authors: Yan Feng, Ting Zhang, Yue Chang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Orthodontic treatment
Periodontal ligament stem cells
N-acetyltransferase 10
N4-acetylcytidine modification
Online Access:https://doi.org/10.1186/s13018-024-05302-w
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