Synthesis and Antibacterial Activity of New Spiro[thiadiazoline-(pyrazolo[3,4-d]pyrimidine)] Derivatives

Synthesis and Antibacterial Activity of New Spiro[thiadiazoline-(pyrazolo[3,4-d]pyrimidine)] Derivatives

New heterocyclic compounds spiroderivatives of allopurinol of biological interest were prepared from allopurinol via thionation and 1,3-dipolar cycloaddition and were produced in high to excellent yields. These compounds were characterized on the b...

Full description

Saved in:

Bibliographic Details
Main Authors:	Mohammed El Fal, Youssef Ramli, Abdelfettah Zerzouf, Ahmed Talbaoui, Youssef Bakri, El Mokhtar Essassi
Format:	Article
Language:	English
Published:	Wiley 2015-01-01
Series:	Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/2015/982404
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

A Facile Synthesis of Pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidine and Pyrido[2′,3′:3,4]pyrazolo[5,1-c][1,2,4]triazine Bearing a Thiophene Moiety
by: Tilal Elsaman, et al.
Published: (2013-01-01)

Design, theoretical approaches and new framework of pyrazolo[3,4-d]pyrimidine as potent anticancer agents: Efficient synthesis, ADME-T and molecular docking
by: Peduri Suresh Reddy, et al.
Published: (2025-03-01)

Synthesis of 1H-pyrazolo[3,4-b]pyridine analogues
by: Yen Nguyen, et al.
Published: (2025-03-01)

Pharmacological Profile of Quinoxalinone
by: Youssef Ramli, et al.
Published: (2014-01-01)

Synthesis and Antibacterial Activity of Chalcones and Pyrimidine-2-ones
by: A. K. Parekh, et al.
Published: (2005-01-01)

Synthesis, Antibacterial and Antioxidant Evaluation of Novel 1-(5,7-Dichloro-1,3-benzoxazol-2-yl)-1H-pyrazolo[3,4-b]quinoline Derivatives
by: N. D. Jayanna, et al.
Published: (2013-01-01)

Studies on Synthesis of Some New Chalcone and Pyrimidines and their Antibacterial Activity
by: Ketan Mistry, et al.
Published: (2005-01-01)

Crystal structure of 1-isopropyl-3-(prop-1-en-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, C11H15N5
by: Wang Yanjiao, et al.
Published: (2022-08-01)

Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents
by: Hafez Hend N., et al.
Published: (2017-09-01)

Thiadiazoline- and Pyrazoline-Based Carboxamides and Carbothioamides: Synthesis and Inhibition against Nitric Oxide Synthase
by: Fabio Arias, et al.
Published: (2018-01-01)

Synthesis and antitumor activity of some novel thiophene, pyrimidine, coumarin, pyrazole and pyridine derivatives
by: Albratty Mohammed, et al.
Published: (2017-03-01)

Synthesis of Some Pyrimidine, Pyrazole, and Pyridine Derivatives and Their Reactivity Descriptors
by: Nour E. A. Abd El-Sattar, et al.
Published: (2018-01-01)

Studies on Synthesis of Pyrimidine Derivatives and their Pharmacological Evaluation
by: T. A. Naik, et al.
Published: (2007-01-01)

Nano-ZnO Catalyzed Multicomponent One-Pot Synthesis of Novel Spiro(indoline-pyranodioxine) Derivatives
by: Harshita Sachdeva, et al.
Published: (2014-01-01)

The crystal structure of bis(pyrazolo[1,5-a]pyrimidine-3-carboxylato-κ2N,O)-copper(ii), C14H8N6O4Cu
by: Hong Dong-Feng, et al.
Published: (2022-08-01)

Corrosion Inhibition Property of Some 1, 3, 4- Thiadiazolines on Mild Steel in Acidic Medium
by: A. Shamitha Begum, et al.
Published: (2010-01-01)

NiO Nanoparticles: An Efficient Catalyst for the Multicomponent One-Pot Synthesis of Novel Spiro and Condensed Indole Derivatives
by: Harshita Sachdeva, et al.
Published: (2013-01-01)

The crystal structure of diaqua-bis(pyrazolo[1,5-a]pyrimidine-3-carboxylato-κ2N,O)manganese(II), C14H12N6O6Mn
by: Hong Dong-Feng, et al.
Published: (2022-08-01)

Synthesis and Antimicrobial Activity of Pyrimidine Salts with Chloranilic and Picric Acids
by: C. Mallikarjunaswamy, et al.
Published: (2013-01-01)

Synthesis and evaluation of antitumor activity of new 4-substituted thieno[3,2-d]pyrimidine and thienotriazolopyrimidine derivatives
by: Hafez Hend N., et al.
Published: (2017-12-01)

Design, synthesis and molecular modeling study of substituted indoline-2-ones and spiro[indole-heterocycles] with potential activity against Gram-positive bacteria
by: Radwan Awwad Abdoh, et al.
Published: (2022-03-01)

Synthesis, Characterization, and Tautomerism of 1,3-Dimethyl Pyrimidine-2,4,6-Trione s-Triazinyl Hydrazine/Hydrazone Derivatives
by: Anamika Sharma, et al.
Published: (2017-01-01)

Superparamagnetic Iron Oxide as an Efficient Catalyst for the One-Pot, Solvent-Free Synthesis of 5,5-Disubstituted Hexahydropyrimidines and Their Spiro Analogues
by: Fatemeh Janati, et al.
Published: (2013-01-01)

ZnO Nanoparticle-Assisted Synthesis of Thiazolo[3,2-α]Pyrimidine Analogs: Antibacterial and Antioxidant Activity, In Silico Molecular Docking, and ADMET Prediction Study
by: Demis Zelelew, et al.
Published: (2022-01-01)

Novel thiazolyl-pyrimidine derivatives as potential anticancer agents: Synthesis, biological evaluation, and molecular docking studies
by: Tariq Z. Abolibda, et al.
Published: (2025-01-01)

Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho[2,1-b]furan-2-yl pyrimidine-2(1H)-one Derivatives
by: Sanjeevan S. Gaikwad, et al.
Published: (2012-01-01)

Thioxopyrimidine in Heterocyclic Synthesis I: Synthesis of Some Novel 6-(Heteroatom-substituted)-(thio)pyrimidine Derivatives
by: Yuh-Wen Ho, et al.
Published: (2013-01-01)

Studies on Synthesis of Some Novel Heterocyclic Chalcone, Pyrazoline, Pyrimidine - 2 - One, Pyrimidine - 2 - Thione, para-Acetanilide Sulphonyl and Benzoyl Derivatives and their Antimicrobial Activity
by: Rakesh N. Mistry, et al.
Published: (2005-01-01)

Spectral Characterization and Antibacterial Activities of Benzyloxybenzaldehydethiosemicarbazone, 3,4-Dihydroxybenzaldehydeisonicotinoylhydrazone and their Transitional Metal Complexes
by: Lakshmi Narayana Suvarapu, et al.
Published: (2011-01-01)

Synthesis of Some New Pyrimidine-Azitidinone Analogues and Their Antioxidant, In Vitro Antimicrobial, and Antitubercular Activities
by: Mallikarjunaswamy Chandrashekaraiah, et al.
Published: (2014-01-01)

Trazendo o Estado de volta à América Latina?
by: Alain El Youssef
Published: (2021-11-01)

Gut-Lung Axis in COVID-19
by: Imane Allali, et al.
Published: (2021-01-01)

Simple approach to thieno[3,2-d]pyrimidines as new scaffolds of antimicrobial activities
by: Hafez Hend N., et al.
Published: (2016-09-01)

Synthesis, <i>In Vitro</i> and <i>In Silico</i> Molecular Docking Studies of Novel Phthalimide–Pyrimidine Hybrid Analogues to Thalidomide as Potent Antitubercular Agents
by: Wael Shehta, et al.
Published: (2025-02-01)

Synthesis of Some Polysubstituted Nicotinonitriles and Derived Pyrido[2,3-d]pyrimidines as In Vitro Cytotoxic and Antimicrobial Candidates
by: Hassan M. Faidallah, et al.
Published: (2016-01-01)

Synthesis, Antibacterial and Antifungal Activities of s Derivatives
by: B. B. Baldaniya, et al.
Published: (2009-01-01)

Pharmacological activities of some triazinopyrazolothieno pyrimidine derivatives
by: Bahashwan Saleh A.
Published: (2017-09-01)

Existence for Elliptic Equation Involving Decaying Cylindrical Potentials with Subcritical and Critical Exponent
by: Mohammed El Mokhtar Ould El Mokhtar
Published: (2015-01-01)

On p-Laplace Equations with Singular Nonlinearities and Critical Sobolev Exponent
by: Mohammed El Mokhtar ould El Mokhtar
Published: (2022-01-01)

Existence and Nonexistence for Boundary Problem Involving the p-Biharmonic Operator and Singular Nonlinearities
by: Mohammed El Mokhtar Ould El Mokhtar
Published: (2023-01-01)