Sterile Endophthalmitis after Intravitreal Injections
Sterile endophthalmitis appears as an infrequent complication of intravitreal injections and seems to develop mainly in the context of the off-label use of drugs that have not been conceived for intravitreous administration. The aetiology of sterile endophthalmitis, independently of the administered...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2012/928123 |
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| author | Joaquín Marticorena Vito Romano Francisco Gómez-Ulla |
| author_facet | Joaquín Marticorena Vito Romano Francisco Gómez-Ulla |
| author_sort | Joaquín Marticorena |
| collection | DOAJ |
| description | Sterile endophthalmitis appears as an infrequent complication of intravitreal injections and seems to develop mainly in the context of the off-label use of drugs that have not been conceived for intravitreous administration. The aetiology of sterile endophthalmitis, independently of the administered drug, remains uncertain and a multifactorial origin cannot be discarded. Sterile inflammation secondary both to intravitreal triamcinolone acetonide and to intravitreal bevacizumab share many characteristics such as the acute and painless vision loss present in the big majority of the cases. Dense vitreous opacity is a common factor, while anterior segment inflammation appears to be mild to moderate. In eyes with sterile endophthalmitis, visual acuity improves progressively as the intraocular inflammation reduces without any specific treatment. If by any chance the ophthalmologist is not convinced by the sterile origin of the inflammation, this complication must be treated as an acute endophthalmitis because of the devastating visual prognosis of this intraocular infection in the absence of therapy. |
| format | Article |
| id | doaj-art-14faf87966d946d39fa0db26b5c0363f |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-14faf87966d946d39fa0db26b5c0363f2025-02-03T06:01:03ZengWileyMediators of Inflammation0962-93511466-18612012-01-01201210.1155/2012/928123928123Sterile Endophthalmitis after Intravitreal InjectionsJoaquín Marticorena0Vito Romano1Francisco Gómez-Ulla2Retina and Vitreous Unit, Instituto Oftlamológico Gómez-Ulla, 15705 Santiago de Compostela, SpainDepartment of Ophthalmology, Second University of Naples, 81100 Naples, ItalyRetina and Vitreous Unit, Instituto Oftlamológico Gómez-Ulla, 15705 Santiago de Compostela, SpainSterile endophthalmitis appears as an infrequent complication of intravitreal injections and seems to develop mainly in the context of the off-label use of drugs that have not been conceived for intravitreous administration. The aetiology of sterile endophthalmitis, independently of the administered drug, remains uncertain and a multifactorial origin cannot be discarded. Sterile inflammation secondary both to intravitreal triamcinolone acetonide and to intravitreal bevacizumab share many characteristics such as the acute and painless vision loss present in the big majority of the cases. Dense vitreous opacity is a common factor, while anterior segment inflammation appears to be mild to moderate. In eyes with sterile endophthalmitis, visual acuity improves progressively as the intraocular inflammation reduces without any specific treatment. If by any chance the ophthalmologist is not convinced by the sterile origin of the inflammation, this complication must be treated as an acute endophthalmitis because of the devastating visual prognosis of this intraocular infection in the absence of therapy.http://dx.doi.org/10.1155/2012/928123 |
| spellingShingle | Joaquín Marticorena Vito Romano Francisco Gómez-Ulla Sterile Endophthalmitis after Intravitreal Injections Mediators of Inflammation |
| title | Sterile Endophthalmitis after Intravitreal Injections |
| title_full | Sterile Endophthalmitis after Intravitreal Injections |
| title_fullStr | Sterile Endophthalmitis after Intravitreal Injections |
| title_full_unstemmed | Sterile Endophthalmitis after Intravitreal Injections |
| title_short | Sterile Endophthalmitis after Intravitreal Injections |
| title_sort | sterile endophthalmitis after intravitreal injections |
| url | http://dx.doi.org/10.1155/2012/928123 |
| work_keys_str_mv | AT joaquinmarticorena sterileendophthalmitisafterintravitrealinjections AT vitoromano sterileendophthalmitisafterintravitrealinjections AT franciscogomezulla sterileendophthalmitisafterintravitrealinjections |