Perfluoropropionic Acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH): Three Conformations and Dimer Formation

Perfluoropropionic acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH) has been investigated with a focus on its complex structural properties. As a formal derivative of propanoic acid, the incorporation of fluorine atoms imparts unique structural features, including three distinct mon...

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Main Authors: Carlos O. Della Védova, Rosana M. Romano, Hans-Georg Stammler, Norbert W. Mitzel
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/9/1887
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author Carlos O. Della Védova
Rosana M. Romano
Hans-Georg Stammler
Norbert W. Mitzel
author_facet Carlos O. Della Védova
Rosana M. Romano
Hans-Georg Stammler
Norbert W. Mitzel
author_sort Carlos O. Della Védova
collection DOAJ
description Perfluoropropionic acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH) has been investigated with a focus on its complex structural properties. As a formal derivative of propanoic acid, the incorporation of fluorine atoms imparts unique structural features, including three distinct monomeric conformations and a dimeric structure. This study presents experimental findings, supported by computational modeling, to explore these characteristics. The analysis includes an FTIR study of the isolated species in an Ar-cryogenic matrix and the low-temperature determination of its crystalline structure using single-crystal X-ray diffraction.
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institution OA Journals
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language English
publishDate 2025-04-01
publisher MDPI AG
record_format Article
series Molecules
spelling doaj-art-14fa6b5c141b4e9f94b869e1fc59d1812025-08-20T02:24:49ZengMDPI AGMolecules1420-30492025-04-01309188710.3390/molecules30091887Perfluoropropionic Acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH): Three Conformations and Dimer FormationCarlos O. Della Védova0Rosana M. Romano1Hans-Georg Stammler2Norbert W. Mitzel3Centro de Química Inorgánica “Dr. Pedro J. Aymonino”, CEQUINOR (Universidad Nacional de La Plata, UNLP, Centro Científico y Tecnológico, Consejo Nacional de Investigaciones Científicas y Técnicas, CCT-CONICET La Plata, Associated with Comisión de Investigaciones Científicas de la Provincia de Buenos Aires, CIC-PBA), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Boulevard 120 N° 1465, La Plata CP 1900, ArgentinaCentro de Química Inorgánica “Dr. Pedro J. Aymonino”, CEQUINOR (Universidad Nacional de La Plata, UNLP, Centro Científico y Tecnológico, Consejo Nacional de Investigaciones Científicas y Técnicas, CCT-CONICET La Plata, Associated with Comisión de Investigaciones Científicas de la Provincia de Buenos Aires, CIC-PBA), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Boulevard 120 N° 1465, La Plata CP 1900, ArgentinaLehrstuhl für Anorganische Chemie und Strukturchemie, Center for Molecular Materials CM2, Bielefeld University, Universitätsstraße 25, 33615 Bielefeld, GermanyLehrstuhl für Anorganische Chemie und Strukturchemie, Center for Molecular Materials CM2, Bielefeld University, Universitätsstraße 25, 33615 Bielefeld, GermanyPerfluoropropionic acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH) has been investigated with a focus on its complex structural properties. As a formal derivative of propanoic acid, the incorporation of fluorine atoms imparts unique structural features, including three distinct monomeric conformations and a dimeric structure. This study presents experimental findings, supported by computational modeling, to explore these characteristics. The analysis includes an FTIR study of the isolated species in an Ar-cryogenic matrix and the low-temperature determination of its crystalline structure using single-crystal X-ray diffraction.https://www.mdpi.com/1420-3049/30/9/1887perfluoropropionic acidlow-temperature crystal structurecryogenic Ar matrix studyconformersmonomersdimer
spellingShingle Carlos O. Della Védova
Rosana M. Romano
Hans-Georg Stammler
Norbert W. Mitzel
Perfluoropropionic Acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH): Three Conformations and Dimer Formation
Molecules
perfluoropropionic acid
low-temperature crystal structure
cryogenic Ar matrix study
conformers
monomers
dimer
title Perfluoropropionic Acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH): Three Conformations and Dimer Formation
title_full Perfluoropropionic Acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH): Three Conformations and Dimer Formation
title_fullStr Perfluoropropionic Acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH): Three Conformations and Dimer Formation
title_full_unstemmed Perfluoropropionic Acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH): Three Conformations and Dimer Formation
title_short Perfluoropropionic Acid (CF<sub>3</sub>CF<sub>2</sub>C(O)OH): Three Conformations and Dimer Formation
title_sort perfluoropropionic acid cf sub 3 sub cf sub 2 sub c o oh three conformations and dimer formation
topic perfluoropropionic acid
low-temperature crystal structure
cryogenic Ar matrix study
conformers
monomers
dimer
url https://www.mdpi.com/1420-3049/30/9/1887
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AT rosanamromano perfluoropropionicacidcfsub3subcfsub2subcoohthreeconformationsanddimerformation
AT hansgeorgstammler perfluoropropionicacidcfsub3subcfsub2subcoohthreeconformationsanddimerformation
AT norbertwmitzel perfluoropropionicacidcfsub3subcfsub2subcoohthreeconformationsanddimerformation