Evidence gaps in conservative non-pharmacological interventions and guideline implementation for high-burden non-communicable diseases: protocol for an overview of reviews

Non-communicable diseases (NCDs) represent a high burden for the society and affected individuals. Conservative non-pharmacological interventions play a first-line role in the treatment and management of most NCDs. Systematic reviews (SRs) provide the highest level of evidence and significantly infl...

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Main Authors: Tobias Braun, Patrick J Owen, Daniel L Belavy, Christian Kopkow, Toni Lange, Tobias Saueressig, Rilind Shala, Jochen Zebisch, Kerstin Lüdtke, Andres Jung, Katja Ehrenbrusthoff, Rebekka Döding, Bernhard Elsner, Clint Miller, Axel Schäfer, Robin Schäfer, Tim Schleimer, Tibor Szikszay
Format: Article
Language:English
Published: BMJ Publishing Group 2024-10-01
Series:BMJ Open Sport & Exercise Medicine
Online Access:https://bmjopensem.bmj.com/content/10/4/e002032.full
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author Tobias Braun
Patrick J Owen
Daniel L Belavy
Christian Kopkow
Toni Lange
Tobias Saueressig
Rilind Shala
Jochen Zebisch
Kerstin Lüdtke
Andres Jung
Katja Ehrenbrusthoff
Rebekka Döding
Bernhard Elsner
Clint Miller
Axel Schäfer
Robin Schäfer
Tim Schleimer
Tibor Szikszay
author_facet Tobias Braun
Patrick J Owen
Daniel L Belavy
Christian Kopkow
Toni Lange
Tobias Saueressig
Rilind Shala
Jochen Zebisch
Kerstin Lüdtke
Andres Jung
Katja Ehrenbrusthoff
Rebekka Döding
Bernhard Elsner
Clint Miller
Axel Schäfer
Robin Schäfer
Tim Schleimer
Tibor Szikszay
author_sort Tobias Braun
collection DOAJ
description Non-communicable diseases (NCDs) represent a high burden for the society and affected individuals. Conservative non-pharmacological interventions play a first-line role in the treatment and management of most NCDs. Systematic reviews (SRs) provide the highest level of evidence and significantly influence clinical decision-making. The primary aim of this study is to provide an overview of the evidence on the effectiveness of recommended conservative non-pharmacological interventions for highly burdensome NCDs. The secondary aim is to provide an overview of the evidence for guideline implementation. A literature search was performed in Medline (PubMed), EMBASE and Cochrane CENTRAL. Six reviewers will, in duplicate, independently screen and select studies following eligibility criteria. The population will include individuals with NCDs from disease categories chosen based on WHO burden of disease data and the importance of conservative rehabilitation for their management. Eligible interventions will encompass conservative non-pharmacological approaches recommended by clinical practice guidelines (ie, physical, psychological and education/advice). Eligible comparator will include no or minimal intervention and other competitive interventions. Outcomes will comprise proposed core outcomes for the respective diseases, including patient-reported (eg, pain) and performance-based (eg, physical functioning) outcomes. SRs published in the last 5 years as peer-reviewed journal article in the English language will be eligible. The overview will be reported in accordance with the Preferred Reporting Items for Overviews of reviews.
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spelling doaj-art-14fa3de707d443d59ef64352d9afd0e52025-08-20T02:17:00ZengBMJ Publishing GroupBMJ Open Sport & Exercise Medicine2055-76472024-10-0110410.1136/bmjsem-2024-002032Evidence gaps in conservative non-pharmacological interventions and guideline implementation for high-burden non-communicable diseases: protocol for an overview of reviewsTobias Braun0Patrick J Owen1Daniel L Belavy2Christian Kopkow3Toni Lange4Tobias Saueressig5Rilind Shala6Jochen Zebisch7Kerstin Lüdtke8Andres Jung9Katja Ehrenbrusthoff10Rebekka Döding11Bernhard Elsner12Clint Miller13Axel Schäfer14Robin Schäfer15Tim Schleimer16Tibor Szikszay17Department of Neurology, University Hospitals Giessen and Marburg Campus Giessen, Giessen, Germany1 Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia1 Institute for Physical Activity and Nutrition, Deakin University, Geelong, Victoria, AustraliaTherapy Sciences, Brandenburg University of Technology Cottbus-Senftenberg, Senftenberg, GermanyFaculty of Medicine and University Hospital Carl Gustav, Center for Evidence-based Healthcare, TU Dresden, Dresden, Germany15 Physio Meets Science GmbH, Leimen, GermanyDepartment of Physiotherapy, Faculty of Medicine, University of Prishtina, Prishtina, KosovoPhysio Meets Science GmbH, Heidelberg, GermanyGerman Society for Physiotherapy Science (Deutsche Gesellschaft für Physiotherapiewissenschaft (DGPTW)), Hamburg, GermanyInstitute of Health Sciences, Department of Physiotherapy, Pain and Exercise Research Luebeck (P.E.R.L), Universität zu Lübeck, Lübeck, GermanyHochschule für Gesundheit, Department of Applied Health Sciences, Division of Physiotherapy, University of Applied Sciences, Bochum, GermanyDepartment of Applied Health Sciences, Division of Physiotherapy, Hochschule für Gesundheit Bochum, Bochum, GermanyInstitute of Health Sciences, Department of Physiotherapy, Universität zu Lübeck, Lubeck, GermanyInstitute for Physical Activity and Nutrition (IPAN), Deakin University, Burwood, Victoria, AustraliaFaculty of Social Work and Health, HAWK, Hildesheim, GermanyDepartment of Applied Health Sciences, Division of Physiotherapy, Hochschule für Gesundheit Bochum, Bochum, GermanyDepartment of Applied Health Sciences, Division of Physiotherapy, Hochschule für Gesundheit Bochum, Bochum, GermanyInstitute of Health Sciences, Department of Physiotherapy, Universität zu Lübeck, Lubeck, GermanyNon-communicable diseases (NCDs) represent a high burden for the society and affected individuals. Conservative non-pharmacological interventions play a first-line role in the treatment and management of most NCDs. Systematic reviews (SRs) provide the highest level of evidence and significantly influence clinical decision-making. The primary aim of this study is to provide an overview of the evidence on the effectiveness of recommended conservative non-pharmacological interventions for highly burdensome NCDs. The secondary aim is to provide an overview of the evidence for guideline implementation. A literature search was performed in Medline (PubMed), EMBASE and Cochrane CENTRAL. Six reviewers will, in duplicate, independently screen and select studies following eligibility criteria. The population will include individuals with NCDs from disease categories chosen based on WHO burden of disease data and the importance of conservative rehabilitation for their management. Eligible interventions will encompass conservative non-pharmacological approaches recommended by clinical practice guidelines (ie, physical, psychological and education/advice). Eligible comparator will include no or minimal intervention and other competitive interventions. Outcomes will comprise proposed core outcomes for the respective diseases, including patient-reported (eg, pain) and performance-based (eg, physical functioning) outcomes. SRs published in the last 5 years as peer-reviewed journal article in the English language will be eligible. The overview will be reported in accordance with the Preferred Reporting Items for Overviews of reviews.https://bmjopensem.bmj.com/content/10/4/e002032.full
spellingShingle Tobias Braun
Patrick J Owen
Daniel L Belavy
Christian Kopkow
Toni Lange
Tobias Saueressig
Rilind Shala
Jochen Zebisch
Kerstin Lüdtke
Andres Jung
Katja Ehrenbrusthoff
Rebekka Döding
Bernhard Elsner
Clint Miller
Axel Schäfer
Robin Schäfer
Tim Schleimer
Tibor Szikszay
Evidence gaps in conservative non-pharmacological interventions and guideline implementation for high-burden non-communicable diseases: protocol for an overview of reviews
BMJ Open Sport & Exercise Medicine
title Evidence gaps in conservative non-pharmacological interventions and guideline implementation for high-burden non-communicable diseases: protocol for an overview of reviews
title_full Evidence gaps in conservative non-pharmacological interventions and guideline implementation for high-burden non-communicable diseases: protocol for an overview of reviews
title_fullStr Evidence gaps in conservative non-pharmacological interventions and guideline implementation for high-burden non-communicable diseases: protocol for an overview of reviews
title_full_unstemmed Evidence gaps in conservative non-pharmacological interventions and guideline implementation for high-burden non-communicable diseases: protocol for an overview of reviews
title_short Evidence gaps in conservative non-pharmacological interventions and guideline implementation for high-burden non-communicable diseases: protocol for an overview of reviews
title_sort evidence gaps in conservative non pharmacological interventions and guideline implementation for high burden non communicable diseases protocol for an overview of reviews
url https://bmjopensem.bmj.com/content/10/4/e002032.full
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