Sleep regularity index as a novel indicator of sleep disturbance in stroke survivors: a secondary data analysis
Abstract Sleep disturbance is common but often overlooked after stroke. Regular sleep is increasingly recognised as important for overall health, yet little is known about how sleep regularity changes after stroke. This study examined differences in the Sleep Regularity Index (SRI) between stroke su...
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Nature Portfolio
2025-05-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-01332-4 |
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| author | Katrijn B. Schruers Matthew Weightman Anna á V. Guttesen Barbara Robinson Heidi Johansen-Berg Melanie K. Fleming |
| author_facet | Katrijn B. Schruers Matthew Weightman Anna á V. Guttesen Barbara Robinson Heidi Johansen-Berg Melanie K. Fleming |
| author_sort | Katrijn B. Schruers |
| collection | DOAJ |
| description | Abstract Sleep disturbance is common but often overlooked after stroke. Regular sleep is increasingly recognised as important for overall health, yet little is known about how sleep regularity changes after stroke. This study examined differences in the Sleep Regularity Index (SRI) between stroke survivors and healthy controls using actigraphy data from an existing dataset (~ 1 week per participant). Data were analysed for 162 stroke survivors (mean age 61 ± 14 years, 5 ± 5 years post-stroke, 89 males) and 60 controls (mean age 57 ± 17 years, 32 males). Stroke survivors had significantly lower SRI scores than controls (p = 0.001), indicating less regular sleep. In the stroke group, higher SRI correlated with longer total sleep time (p = 0.003) and better self-reported sleep quality (p = 0.001) but not with other sleep metrics. Lower SRI was associated with worse depressive symptoms (p = 0.006) and lower quality of life (p = 0.001) but not with disability (p = 0.886) or time since stroke (p = 0.646). These findings suggest that sleep regularity is disrupted post-stroke and may influence well-being. Future research should explore interventions to improve sleep regularity and related health outcomes in stroke survivors. |
| format | Article |
| id | doaj-art-14f6b2693e444197a45bcd2beb4716d5 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-14f6b2693e444197a45bcd2beb4716d52025-08-20T03:48:19ZengNature PortfolioScientific Reports2045-23222025-05-0115111210.1038/s41598-025-01332-4Sleep regularity index as a novel indicator of sleep disturbance in stroke survivors: a secondary data analysisKatrijn B. Schruers0Matthew Weightman1Anna á V. Guttesen2Barbara Robinson3Heidi Johansen-Berg4Melanie K. Fleming5Nuffield Department of Clinical Neurosciences, Wellcome Centre for Integrative Neuroimaging (WIN), FMRIB, John Radcliffe Hospital, University of OxfordNuffield Department of Clinical Neurosciences, Wellcome Centre for Integrative Neuroimaging (WIN), FMRIB, John Radcliffe Hospital, University of OxfordNuffield Department of Clinical Neurosciences, Wellcome Centre for Integrative Neuroimaging (WIN), FMRIB, John Radcliffe Hospital, University of OxfordNuffield Department of Clinical Neurosciences, Wellcome Centre for Integrative Neuroimaging (WIN), FMRIB, John Radcliffe Hospital, University of OxfordNuffield Department of Clinical Neurosciences, Wellcome Centre for Integrative Neuroimaging (WIN), FMRIB, John Radcliffe Hospital, University of OxfordNuffield Department of Clinical Neurosciences, Wellcome Centre for Integrative Neuroimaging (WIN), FMRIB, John Radcliffe Hospital, University of OxfordAbstract Sleep disturbance is common but often overlooked after stroke. Regular sleep is increasingly recognised as important for overall health, yet little is known about how sleep regularity changes after stroke. This study examined differences in the Sleep Regularity Index (SRI) between stroke survivors and healthy controls using actigraphy data from an existing dataset (~ 1 week per participant). Data were analysed for 162 stroke survivors (mean age 61 ± 14 years, 5 ± 5 years post-stroke, 89 males) and 60 controls (mean age 57 ± 17 years, 32 males). Stroke survivors had significantly lower SRI scores than controls (p = 0.001), indicating less regular sleep. In the stroke group, higher SRI correlated with longer total sleep time (p = 0.003) and better self-reported sleep quality (p = 0.001) but not with other sleep metrics. Lower SRI was associated with worse depressive symptoms (p = 0.006) and lower quality of life (p = 0.001) but not with disability (p = 0.886) or time since stroke (p = 0.646). These findings suggest that sleep regularity is disrupted post-stroke and may influence well-being. Future research should explore interventions to improve sleep regularity and related health outcomes in stroke survivors.https://doi.org/10.1038/s41598-025-01332-4ActigraphySleep-wake patternsCircadian rhythmQuality of lifePost-stroke recovery |
| spellingShingle | Katrijn B. Schruers Matthew Weightman Anna á V. Guttesen Barbara Robinson Heidi Johansen-Berg Melanie K. Fleming Sleep regularity index as a novel indicator of sleep disturbance in stroke survivors: a secondary data analysis Scientific Reports Actigraphy Sleep-wake patterns Circadian rhythm Quality of life Post-stroke recovery |
| title | Sleep regularity index as a novel indicator of sleep disturbance in stroke survivors: a secondary data analysis |
| title_full | Sleep regularity index as a novel indicator of sleep disturbance in stroke survivors: a secondary data analysis |
| title_fullStr | Sleep regularity index as a novel indicator of sleep disturbance in stroke survivors: a secondary data analysis |
| title_full_unstemmed | Sleep regularity index as a novel indicator of sleep disturbance in stroke survivors: a secondary data analysis |
| title_short | Sleep regularity index as a novel indicator of sleep disturbance in stroke survivors: a secondary data analysis |
| title_sort | sleep regularity index as a novel indicator of sleep disturbance in stroke survivors a secondary data analysis |
| topic | Actigraphy Sleep-wake patterns Circadian rhythm Quality of life Post-stroke recovery |
| url | https://doi.org/10.1038/s41598-025-01332-4 |
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