Quantitative determination of phenazepam and its active metabolite in human blood plasma at different extraction procedures

Introduction. The presence of the active metabolite (3-hydroxyphenazepam, 3-OH-PHEN), the wide interindividual variability of the therapeutic effect of phenazepam (PHEN), as well as its active moiety in the blood, determine the relevance of therapeutic drug monitoring (TDM). To do this, the research...

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Bibliographic Details
Main Authors: I. I. Miroshnichenko, A. I. Platova, I. I. Kuzmin, D. V. Ivaschenko
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2024-09-01
Series:Разработка и регистрация лекарственных средств
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Online Access:https://www.pharmjournal.ru/jour/article/view/1911
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