Comparative Analysis of Vascular Cell Differentiation From Peripheral Blood Mononuclear Cell- and Urine-Derived Induced Pluripotent Stem Cells

Conclusions: This study presents a comprehensive comparative analysis of functionally differentiated ECs and VSMCs derived from PiPSCs and UiPSCs, providing critical insights into the expression patterns and phenotypic transitions during differentiation. Our findings enhance the understanding of dis...

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Main Authors: Julia Deinsberger, Silvio Holzner, Sophie Bromberger, Philipp Foessleitner, Dominik Wiedemann, Bernhard Winkler, Natalia Krajic, Sophia Aligianni, Elisabeth Stein, Jennifer Volz, Zahra Mazidi, Regina Grillari, Klaudia Schossleitner, Peter Petzelbauer, Benedikt Weber
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2024/9603094
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author Julia Deinsberger
Silvio Holzner
Sophie Bromberger
Philipp Foessleitner
Dominik Wiedemann
Bernhard Winkler
Natalia Krajic
Sophia Aligianni
Elisabeth Stein
Jennifer Volz
Zahra Mazidi
Regina Grillari
Klaudia Schossleitner
Peter Petzelbauer
Benedikt Weber
author_facet Julia Deinsberger
Silvio Holzner
Sophie Bromberger
Philipp Foessleitner
Dominik Wiedemann
Bernhard Winkler
Natalia Krajic
Sophia Aligianni
Elisabeth Stein
Jennifer Volz
Zahra Mazidi
Regina Grillari
Klaudia Schossleitner
Peter Petzelbauer
Benedikt Weber
author_sort Julia Deinsberger
collection DOAJ
description Conclusions: This study presents a comprehensive comparative analysis of functionally differentiated ECs and VSMCs derived from PiPSCs and UiPSCs, providing critical insights into the expression patterns and phenotypic transitions during differentiation. Our findings enhance the understanding of distinct molecular signatures in iPSCs from different sources and their progeny.
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issn 1687-9678
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publishDate 2024-01-01
publisher Wiley
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series Stem Cells International
spelling doaj-art-14ea45ca24e749fc92369b94e1c2c7892025-08-20T03:17:22ZengWileyStem Cells International1687-96782024-01-01202410.1155/2024/9603094Comparative Analysis of Vascular Cell Differentiation From Peripheral Blood Mononuclear Cell- and Urine-Derived Induced Pluripotent Stem CellsJulia Deinsberger0Silvio Holzner1Sophie Bromberger2Philipp Foessleitner3Dominik Wiedemann4Bernhard Winkler5Natalia Krajic6Sophia Aligianni7Elisabeth Stein8Jennifer Volz9Zahra Mazidi10Regina Grillari11Klaudia Schossleitner12Peter Petzelbauer13Benedikt Weber14Department of DermatologyDepartment of DermatologyDepartment of DermatologyDepartment of Obstetrics and GynecologyDepartment of Cardiac SurgeryDepartment of Cardiovascular SurgeryDepartment of DermatologyIMBA—Institute of Molecular Biotechnology of the Austrian Academy of SciencesIMBA—Institute of Molecular Biotechnology of the Austrian Academy of SciencesIMBA—Institute of Molecular Biotechnology of the Austrian Academy of SciencesEvercyte GmbHEvercyte GmbHDepartment of DermatologyDepartment of DermatologyDepartment of DermatologyConclusions: This study presents a comprehensive comparative analysis of functionally differentiated ECs and VSMCs derived from PiPSCs and UiPSCs, providing critical insights into the expression patterns and phenotypic transitions during differentiation. Our findings enhance the understanding of distinct molecular signatures in iPSCs from different sources and their progeny.http://dx.doi.org/10.1155/2024/9603094
spellingShingle Julia Deinsberger
Silvio Holzner
Sophie Bromberger
Philipp Foessleitner
Dominik Wiedemann
Bernhard Winkler
Natalia Krajic
Sophia Aligianni
Elisabeth Stein
Jennifer Volz
Zahra Mazidi
Regina Grillari
Klaudia Schossleitner
Peter Petzelbauer
Benedikt Weber
Comparative Analysis of Vascular Cell Differentiation From Peripheral Blood Mononuclear Cell- and Urine-Derived Induced Pluripotent Stem Cells
Stem Cells International
title Comparative Analysis of Vascular Cell Differentiation From Peripheral Blood Mononuclear Cell- and Urine-Derived Induced Pluripotent Stem Cells
title_full Comparative Analysis of Vascular Cell Differentiation From Peripheral Blood Mononuclear Cell- and Urine-Derived Induced Pluripotent Stem Cells
title_fullStr Comparative Analysis of Vascular Cell Differentiation From Peripheral Blood Mononuclear Cell- and Urine-Derived Induced Pluripotent Stem Cells
title_full_unstemmed Comparative Analysis of Vascular Cell Differentiation From Peripheral Blood Mononuclear Cell- and Urine-Derived Induced Pluripotent Stem Cells
title_short Comparative Analysis of Vascular Cell Differentiation From Peripheral Blood Mononuclear Cell- and Urine-Derived Induced Pluripotent Stem Cells
title_sort comparative analysis of vascular cell differentiation from peripheral blood mononuclear cell and urine derived induced pluripotent stem cells
url http://dx.doi.org/10.1155/2024/9603094
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