Impact of Amerindian ancestry on clinical outcomes in Crohn’s disease and ulcerative colitis in a Latino population

Impact of Amerindian ancestry on clinical outcomes in Crohn’s disease and ulcerative colitis in a Latino population

Abstract Research in Inflammatory Bowel Disease (IBD) assessing the genetic structure and its association with IBD phenotypes is needed, especially in IBD-underrepresented populations such as the South American IBD population. Aim. We examine the correlation between Amerindian ancestry and IBD pheno...

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Main Authors: Tamara Pérez-Jeldres, María Leonor Bustamante, Danilo Alvares, Manuel Alvarez-Lobos, Lajos Kalmer, Lorena Azocar, Roberto Segovia Melero, Gabriel Ascui, Nataly Aguilar, Ricardo Estela, Cristian Hernández-Rocha, Roberto Candia, Mauricio González, Verónica Silva, Andrés De La Vega, Elizabeth Arriagada, Carolina A. Serrano, Carolina Pávez-Ovalle, Carol Moraga Quinteros, Juan Francisco Miquel, Di Genova Alex
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Inflammatory bowel disease
Ancestry
South America
Online Access:https://doi.org/10.1038/s41598-025-99543-2
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