Elevated plasma levels of WAP four-disulfide core domain 2 as a potential prognostic biomarker for various cancers

Elevated plasma levels of WAP four-disulfide core domain 2 as a potential prognostic biomarker for various cancers

BackgroundAlthough WAP four-disulfide core domain 2 (WFDC2) is widely recognized as a diagnostic biomarker for ovarian cancer, its function in other cancer types remains unclear. The aim of this study was to evaluate the prognostic potential of WFDC2 across multiple cancers.MethodsPublicly available...

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Main Authors: Makoto Watanabe, Katsuaki Ieguchi, Nobuyuki Onishi, Takashi Shimizu, Ryotaro Ohkuma, Risako Suzuki, Emiko Mura, Nana Iriguchi, Tomoyuki Ishiguro, Yuya Hirasawa, Go Ikeda, Masahiro Shimokawa, Hirotsugu Ariizumi, Atsushi Horiike, Kiyoshi Yoshimura, Takuya Tsunoda, Mayumi Tsuji, Shinichi Kobayashi, Yuji Kiuchi, Satoshi Wada
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Oncology
Subjects:
WFDC2
biomarker
plasma
ELISA
cancer prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1614102/full
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https://www.frontiersin.org/articles/10.3389/fonc.2025.1614102/full

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