Exploratory Review and In Silico Insights into circRNA and RNA-Binding Protein Roles in γ-Globin to β-Globin Switching
β-globin gene cluster regulation involves complex mechanisms to ensure proper expression and function in RBCs. During development, switching occurs as γ-globin is replaced by β-globin. Key regulators, like BCL11A and ZBTB7A, repress γ-globin expression to facilitate this transition with other factor...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-02-01
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| Series: | Cells |
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| Online Access: | https://www.mdpi.com/2073-4409/14/4/312 |
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