Reirradiation based on diffusion-weighted magnetic resonance imaging-guided dose- painting for locally advanced recurrent nasopharyngeal carcinoma: a phase 2 randomized controlled trial

Reirradiation based on diffusion-weighted magnetic resonance imaging-guided dose- painting for locally advanced recurrent nasopharyngeal carcinoma: a phase 2 randomized controlled trial

Abstract Introduction The effect of diffusion-weighted magnetic resonance imaging (DWI)-guided dose-painting intensity-modulated radiation therapy (DP-IMRT) on locally advanced recurrent nasopharyngeal carcinoma (NPC) remains unclear. This study aimed to compare the outcomes and toxicities of DWI-gu...

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Bibliographic Details
Main Authors: Chao Tan, Yuyi Li, Xiaoyu Chen, Weichang Zhu, Cuihong Jiang, Lili He, Shuai Xiao, Changgen Fan, Xu Ye, Qi Zhao, Wenqiong Wu, Yanxian Li, Yanfang Qiu, Kailin Chen, Shulu Hu, Feng Liu, Hui Wang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
Subjects:
Recurrent NPC
Reirradiation (ReRT)
DWI (diffusion weighted imaging)
IMRT (intensity modulated radiation therapy)
Toxicicity
Online Access:https://doi.org/10.1186/s12885-025-13969-5
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