Severe Alveolar Bone Loss as a Rare Manifestation of Suspected Intestinal Behçet Disease: A Case Report

Oral ulcers commonly occur in Behçet disease, but severe alveolar bone loss is rarely documented. We report a case where marked periodontal destruction preceded the diagnosis of suspected intestinal Behçet disease. A 21-year-old man presented with extensive palatal ulcers and severe maxillary alveol...

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Main Authors: Satoru Morikawa, DDS, PhD, Yuta Kaieda, MD, Satoshi Usuda, DDS, Kazuyuki Tsunoda, DDS, PhD, Takanori Kanai, MD, PhD, Taneaki Nakagawa, DDS, PhD
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Online Access:http://www.sciencedirect.com/science/article/pii/S2542454825000232
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Summary:Oral ulcers commonly occur in Behçet disease, but severe alveolar bone loss is rarely documented. We report a case where marked periodontal destruction preceded the diagnosis of suspected intestinal Behçet disease. A 21-year-old man presented with extensive palatal ulcers and severe maxillary alveolar bone loss extending to the root apices. Radiographic examination revealed localized bone destruction confined to the palatal region. Subsequent evaluation revealed intestinal lesions characteristic of Behçet disease. A combination of systemic medications (prednisolone, mesalazine, and infliximab) and periodontal care stabilized both oral and intestinal conditions. This case highlights that severe alveolar bone destruction can manifest as a complication of intestinal Behçet disease, underscoring the importance of thorough oral examinations and integrated medical-dental care.
ISSN:2542-4548