Juvenile Idiopathic Arthritis Subtype- and Sex-specific Associations with Genetic Variants in the PSMA6/PSMC6/PSMA3 Gene Cluster

Juvenile Idiopathic Arthritis Subtype- and Sex-specific Associations with Genetic Variants in the PSMA6/PSMC6/PSMA3 Gene Cluster

The ubiquitin proteasome system plays an exceptional biological role in the antigen processing and immune response and it could potentially be involved in pathogenesis of many immunity-related diseases, including juvenile idiopathic arthritis (JIA). Methods: The PSMB5 (rs11543947), PSMA6 (rs2277460,...

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Bibliographic Details
Main Authors: Tatjana Sjakste, Natalia Paramonova, Ingrida Rumba-Rozenfelde, Ilva Trapina, Olga Sugoka, Nikolajs Sjakste
Format: Article
Language:English
Published: Elsevier 2014-10-01
Series:Pediatrics and Neonatology
Subjects:
genotype–sex interaction
juvenile idiopathic arthritis
plasma proteasome
polymorphism
PSMA3
PSMA6
PSMC6
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957214000631
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