Reversible Vitamin B12 Deficiency Presenting with Acute Dementia, Paraparesis, and Normal Hemoglobin
Vitamin B12 is essential for neurological function and its deficiency is associated with many neuropsychiatric disorders. We report the case of a previously healthy 53-year-old male patient presenting with delirium and multiple neurological findings. Complete blood analysis indicated megaloblastic a...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/4301769 |
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| author | Hani Almoallim Fahtima S. Mehdawi Mohammed M. Cheikh Fahmi Al-dhaheri Abdullah Mahir Aqeel |
| author_facet | Hani Almoallim Fahtima S. Mehdawi Mohammed M. Cheikh Fahmi Al-dhaheri Abdullah Mahir Aqeel |
| author_sort | Hani Almoallim |
| collection | DOAJ |
| description | Vitamin B12 is essential for neurological function and its deficiency is associated with many neuropsychiatric disorders. We report the case of a previously healthy 53-year-old male patient presenting with delirium and multiple neurological findings. Complete blood analysis indicated megaloblastic anemia. All infectious causes were excluded owing to negative cultures (blood and urine). Tests for human immunodeficiency virus, syphilis, and toxoplasma were also negative. Metabolic workup showed severe vitamin B12 deficiency, decreased reticulocyte count, and increased direct bilirubin and lactate dehydrogenase. Intramuscular injection of cobalamin was started, and the patient showed significant improvement. |
| format | Article |
| id | doaj-art-14beadce6d90496793e125ab16f5bc96 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-14beadce6d90496793e125ab16f5bc962025-02-03T06:06:22ZengWileyCase Reports in Neurological Medicine2090-66682090-66762016-01-01201610.1155/2016/43017694301769Reversible Vitamin B12 Deficiency Presenting with Acute Dementia, Paraparesis, and Normal HemoglobinHani Almoallim0Fahtima S. Mehdawi1Mohammed M. Cheikh2Fahmi Al-dhaheri3Abdullah Mahir Aqeel4Alzaidi Chair of Research, Department of Medicine, Umm Al-Qura University, Makkah, Saudi ArabiaDepartment of Medicine, Soliman Fakeeh Hospital, Jeddah, Saudi ArabiaDepartment of Medicine, Soliman Fakeeh Hospital, Jeddah, Saudi ArabiaDepartment of Medicine, Soliman Fakeeh Hospital, Jeddah, Saudi ArabiaUmm Al-Qura University, Makkah, Saudi ArabiaVitamin B12 is essential for neurological function and its deficiency is associated with many neuropsychiatric disorders. We report the case of a previously healthy 53-year-old male patient presenting with delirium and multiple neurological findings. Complete blood analysis indicated megaloblastic anemia. All infectious causes were excluded owing to negative cultures (blood and urine). Tests for human immunodeficiency virus, syphilis, and toxoplasma were also negative. Metabolic workup showed severe vitamin B12 deficiency, decreased reticulocyte count, and increased direct bilirubin and lactate dehydrogenase. Intramuscular injection of cobalamin was started, and the patient showed significant improvement.http://dx.doi.org/10.1155/2016/4301769 |
| spellingShingle | Hani Almoallim Fahtima S. Mehdawi Mohammed M. Cheikh Fahmi Al-dhaheri Abdullah Mahir Aqeel Reversible Vitamin B12 Deficiency Presenting with Acute Dementia, Paraparesis, and Normal Hemoglobin Case Reports in Neurological Medicine |
| title | Reversible Vitamin B12 Deficiency Presenting with Acute Dementia, Paraparesis, and Normal Hemoglobin |
| title_full | Reversible Vitamin B12 Deficiency Presenting with Acute Dementia, Paraparesis, and Normal Hemoglobin |
| title_fullStr | Reversible Vitamin B12 Deficiency Presenting with Acute Dementia, Paraparesis, and Normal Hemoglobin |
| title_full_unstemmed | Reversible Vitamin B12 Deficiency Presenting with Acute Dementia, Paraparesis, and Normal Hemoglobin |
| title_short | Reversible Vitamin B12 Deficiency Presenting with Acute Dementia, Paraparesis, and Normal Hemoglobin |
| title_sort | reversible vitamin b12 deficiency presenting with acute dementia paraparesis and normal hemoglobin |
| url | http://dx.doi.org/10.1155/2016/4301769 |
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