Prevalence, Risk Factors of Preserved Ratio Impaired Spirometry in adult in plateau: A Cross-Sectional Study.
<h4>Background</h4>Preserved ratio impaired spirometry(PRISm) is considered to be a precursor of COPD. The purpose of our study is to investigate the prevalence and risk factors of PRISm in high-altitude areas.<h4>Methods</h4>The adult residents of Hongyuan County were select...
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0318546 |
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| author | Junjie Xia Yu Qiu Ling Huang Wenjun Li Xingxiong Zou Xiaoqian Wang Xiaoli Hou Yuting Chen Haishi Xue Runjiao Chen Lingna Li Ke Yi Jincheng Wang Wenying Xie |
| author_facet | Junjie Xia Yu Qiu Ling Huang Wenjun Li Xingxiong Zou Xiaoqian Wang Xiaoli Hou Yuting Chen Haishi Xue Runjiao Chen Lingna Li Ke Yi Jincheng Wang Wenying Xie |
| author_sort | Junjie Xia |
| collection | DOAJ |
| description | <h4>Background</h4>Preserved ratio impaired spirometry(PRISm) is considered to be a precursor of COPD. The purpose of our study is to investigate the prevalence and risk factors of PRISm in high-altitude areas.<h4>Methods</h4>The adult residents of Hongyuan County were selected by random sampling method, and the lung function tests, questionnaires, blood tests were conducted. The prevalence of PRISm was compared among different factors of investigation, and binary logistic regression analysis was used to determine the independent influencing factors of PRISm.<h4>Results</h4>627 participants qualified for quality control, the prevalence was 10.06%. The independent factors of PRISm were age 40-49 years old(OR = 4.322,95%CI: 1.149-16.262),age ≧ 60 years (OR = 4.453, 95% CI: 1.003-19.762),Body mass index ≧ 30(OR: 3.745, 95% CI: 1.611-8.707),Smoking (OR: 2.591, 95% CI: 1.305-5.146), Diabetes (OR: 3.894, 95% CI: 1.043-14.199), history of pulmonary tuberculosis (OR: 13.678, 95% CI: 5.495-34.049), hypertension(OR: 3.447, 95% CI: 1.529-7.771), White blood cell count(OR: 1.414, 95% CI: 1.164-1.717), and Red blood cell volume distribution width (OR: 1.098, 95% CI: 1.009-1.196).<h4>Conclusion</h4>The prevalence of PRISm in Hongyuan County was 10.03%; The independent influencing factors of PRISm included age, smoking, the history of tuberculosis, diabetes,hypertension,body mass index ≧ 30,Red blood cell volume distribution width. |
| format | Article |
| id | doaj-art-14b91d3f00fd4590b9031bc2c0d3746d |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-14b91d3f00fd4590b9031bc2c0d3746d2025-08-20T03:53:38ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01204e031854610.1371/journal.pone.0318546Prevalence, Risk Factors of Preserved Ratio Impaired Spirometry in adult in plateau: A Cross-Sectional Study.Junjie XiaYu QiuLing HuangWenjun LiXingxiong ZouXiaoqian WangXiaoli HouYuting ChenHaishi XueRunjiao ChenLingna LiKe YiJincheng WangWenying Xie<h4>Background</h4>Preserved ratio impaired spirometry(PRISm) is considered to be a precursor of COPD. The purpose of our study is to investigate the prevalence and risk factors of PRISm in high-altitude areas.<h4>Methods</h4>The adult residents of Hongyuan County were selected by random sampling method, and the lung function tests, questionnaires, blood tests were conducted. The prevalence of PRISm was compared among different factors of investigation, and binary logistic regression analysis was used to determine the independent influencing factors of PRISm.<h4>Results</h4>627 participants qualified for quality control, the prevalence was 10.06%. The independent factors of PRISm were age 40-49 years old(OR = 4.322,95%CI: 1.149-16.262),age ≧ 60 years (OR = 4.453, 95% CI: 1.003-19.762),Body mass index ≧ 30(OR: 3.745, 95% CI: 1.611-8.707),Smoking (OR: 2.591, 95% CI: 1.305-5.146), Diabetes (OR: 3.894, 95% CI: 1.043-14.199), history of pulmonary tuberculosis (OR: 13.678, 95% CI: 5.495-34.049), hypertension(OR: 3.447, 95% CI: 1.529-7.771), White blood cell count(OR: 1.414, 95% CI: 1.164-1.717), and Red blood cell volume distribution width (OR: 1.098, 95% CI: 1.009-1.196).<h4>Conclusion</h4>The prevalence of PRISm in Hongyuan County was 10.03%; The independent influencing factors of PRISm included age, smoking, the history of tuberculosis, diabetes,hypertension,body mass index ≧ 30,Red blood cell volume distribution width.https://doi.org/10.1371/journal.pone.0318546 |
| spellingShingle | Junjie Xia Yu Qiu Ling Huang Wenjun Li Xingxiong Zou Xiaoqian Wang Xiaoli Hou Yuting Chen Haishi Xue Runjiao Chen Lingna Li Ke Yi Jincheng Wang Wenying Xie Prevalence, Risk Factors of Preserved Ratio Impaired Spirometry in adult in plateau: A Cross-Sectional Study. PLoS ONE |
| title | Prevalence, Risk Factors of Preserved Ratio Impaired Spirometry in adult in plateau: A Cross-Sectional Study. |
| title_full | Prevalence, Risk Factors of Preserved Ratio Impaired Spirometry in adult in plateau: A Cross-Sectional Study. |
| title_fullStr | Prevalence, Risk Factors of Preserved Ratio Impaired Spirometry in adult in plateau: A Cross-Sectional Study. |
| title_full_unstemmed | Prevalence, Risk Factors of Preserved Ratio Impaired Spirometry in adult in plateau: A Cross-Sectional Study. |
| title_short | Prevalence, Risk Factors of Preserved Ratio Impaired Spirometry in adult in plateau: A Cross-Sectional Study. |
| title_sort | prevalence risk factors of preserved ratio impaired spirometry in adult in plateau a cross sectional study |
| url | https://doi.org/10.1371/journal.pone.0318546 |
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