Characterization of Bacterial Strains and Their Resistance Status in the Hospital Environment: Systematic Review
Background: Clinical environments are considered reservoirs of antibiotic-resistant microorganisms that lead to the constant progression of nosocomial infections. The objective of this systematic review is to provide an epidemiological description of the role of the hospital environment as a reservo...
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| Format: | Article |
| Language: | English |
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Bucharest College of Physicians
2025-03-01
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| Series: | Modern Medicine |
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| Online Access: | https://medicinamoderna.ro/wp-content/uploads/2025/03/Characterization-of-Bacterial-Strains-and-Their-Resistance-Status-in-the-Hospital-Environment-S.pdf |
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| author | Diego Alejandro ESTRADA RIOS Isabela MUÑOZ ARIAS Alvaro Javier CASTELLANOS GARCÍA Monica CHAVEZ VIVAS |
| author_facet | Diego Alejandro ESTRADA RIOS Isabela MUÑOZ ARIAS Alvaro Javier CASTELLANOS GARCÍA Monica CHAVEZ VIVAS |
| author_sort | Diego Alejandro ESTRADA RIOS |
| collection | DOAJ |
| description | Background: Clinical environments are considered reservoirs of antibiotic-resistant microorganisms that lead to the constant progression of nosocomial infections. The objective of this systematic review is to provide an epidemiological description of the role of the hospital environment as a reservoir of antibiotic-resistant bacteria and antibiotic-resistance genes. Materials and Method: A systematic review based on the PRISMA guide was carried out, from the Science Direct, Redalyc, Scopus, Hinari, Scielo, Dialnet, PLOS, ProQuest, Taylor, Lilacs and PubMed databases with original studies conducted between January 2013-July 2024. Results: A total of 1751 studies were identified, but only 60 studies were considered eligible for inclusión. The most common hospital environment sample sources were inanimate surfaces and medical devices and implements. extended-spectrum β-lactamases-producing Enterobacteriaceae, Methicillin-resistant Staphylococcus aureus and carbapenemase-producing non-fermenting bacilli as the main organisms found in the hospital environment mediated mainly by bla genes. Multidrug-resistant organisms were identified as the most abundant type in most samples, largely due to the ubiquity of efflux pumps (acr, mex, mdt and emr). Conclusion: Our systematic review reveals the hospital environment is an ecological niche with predominance of few clones with a high degree of multi-resistance to antibiotics that contributes to generate new clones that spread through inanimate surfaces and equipment. |
| format | Article |
| id | doaj-art-14b24cedd59742feabcbd08ff30888ac |
| institution | DOAJ |
| issn | 1223-0472 2360-2473 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Bucharest College of Physicians |
| record_format | Article |
| series | Modern Medicine |
| spelling | doaj-art-14b24cedd59742feabcbd08ff30888ac2025-08-20T03:08:51ZengBucharest College of PhysiciansModern Medicine1223-04722360-24732025-03-01321233510.31689/rmm.2025.32.1.23Characterization of Bacterial Strains and Their Resistance Status in the Hospital Environment: Systematic ReviewDiego Alejandro ESTRADA RIOS0Isabela MUÑOZ ARIAS1Alvaro Javier CASTELLANOS GARCÍA2Monica CHAVEZ VIVAS3Faculty of Health Sciences, Universidad Libre, seccional Cali-Colombia, ColombiaFaculty of Health Sciences, Universidad Libre, seccional Cali-Colombia, ColombiaFaculty of Health Sciences, Universidad Libre, seccional Cali-Colombia, ColombiaHealth Sciences Faculty, Universidad Libre, GIMMEIN research group, ColombiaBackground: Clinical environments are considered reservoirs of antibiotic-resistant microorganisms that lead to the constant progression of nosocomial infections. The objective of this systematic review is to provide an epidemiological description of the role of the hospital environment as a reservoir of antibiotic-resistant bacteria and antibiotic-resistance genes. Materials and Method: A systematic review based on the PRISMA guide was carried out, from the Science Direct, Redalyc, Scopus, Hinari, Scielo, Dialnet, PLOS, ProQuest, Taylor, Lilacs and PubMed databases with original studies conducted between January 2013-July 2024. Results: A total of 1751 studies were identified, but only 60 studies were considered eligible for inclusión. The most common hospital environment sample sources were inanimate surfaces and medical devices and implements. extended-spectrum β-lactamases-producing Enterobacteriaceae, Methicillin-resistant Staphylococcus aureus and carbapenemase-producing non-fermenting bacilli as the main organisms found in the hospital environment mediated mainly by bla genes. Multidrug-resistant organisms were identified as the most abundant type in most samples, largely due to the ubiquity of efflux pumps (acr, mex, mdt and emr). Conclusion: Our systematic review reveals the hospital environment is an ecological niche with predominance of few clones with a high degree of multi-resistance to antibiotics that contributes to generate new clones that spread through inanimate surfaces and equipment.https://medicinamoderna.ro/wp-content/uploads/2025/03/Characterization-of-Bacterial-Strains-and-Their-Resistance-Status-in-the-Hospital-Environment-S.pdfantibiotic-resistant bacteriaresistance geneshospitalsenvironmentequipment contamination |
| spellingShingle | Diego Alejandro ESTRADA RIOS Isabela MUÑOZ ARIAS Alvaro Javier CASTELLANOS GARCÍA Monica CHAVEZ VIVAS Characterization of Bacterial Strains and Their Resistance Status in the Hospital Environment: Systematic Review Modern Medicine antibiotic-resistant bacteria resistance genes hospitals environment equipment contamination |
| title | Characterization of Bacterial Strains and Their Resistance Status in the Hospital Environment: Systematic Review |
| title_full | Characterization of Bacterial Strains and Their Resistance Status in the Hospital Environment: Systematic Review |
| title_fullStr | Characterization of Bacterial Strains and Their Resistance Status in the Hospital Environment: Systematic Review |
| title_full_unstemmed | Characterization of Bacterial Strains and Their Resistance Status in the Hospital Environment: Systematic Review |
| title_short | Characterization of Bacterial Strains and Their Resistance Status in the Hospital Environment: Systematic Review |
| title_sort | characterization of bacterial strains and their resistance status in the hospital environment systematic review |
| topic | antibiotic-resistant bacteria resistance genes hospitals environment equipment contamination |
| url | https://medicinamoderna.ro/wp-content/uploads/2025/03/Characterization-of-Bacterial-Strains-and-Their-Resistance-Status-in-the-Hospital-Environment-S.pdf |
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