Bifidobacterium Longum: Protection against Inflammatory Bowel Disease
The prevalence of inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), increases gradually worldwide in the past decades. IBD is generally associated with the change of the immune system and gut microbiota, and the conventional treatments usually result...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2021/8030297 |
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| _version_ | 1849308277098151936 |
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| author | Shunyu Yao Zixi Zhao Weijun Wang Xiaolu Liu |
| author_facet | Shunyu Yao Zixi Zhao Weijun Wang Xiaolu Liu |
| author_sort | Shunyu Yao |
| collection | DOAJ |
| description | The prevalence of inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), increases gradually worldwide in the past decades. IBD is generally associated with the change of the immune system and gut microbiota, and the conventional treatments usually result in some side effects. Bifidobacterium longum, as colonizing bacteria in the intestine, has been demonstrated to be capable of relieving colitis in mice and can be employed as an alternative or auxiliary way for treating IBD. Here, the mechanisms of the Bifidobacterium longum in the treatment of IBD were summarized based on previous cell and animal studies and clinical trials testing bacterial therapies. This review will be served as a basis for future research on IBD treatment. |
| format | Article |
| id | doaj-art-14af4595fdb044f89efc9cc685cdbf42 |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-14af4595fdb044f89efc9cc685cdbf422025-08-20T03:54:29ZengWileyJournal of Immunology Research2314-88612314-71562021-01-01202110.1155/2021/80302978030297Bifidobacterium Longum: Protection against Inflammatory Bowel DiseaseShunyu Yao0Zixi Zhao1Weijun Wang2Xiaolu Liu3School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaSchool of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaSchool of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaSchool of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, ChinaThe prevalence of inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn’s disease (CD), increases gradually worldwide in the past decades. IBD is generally associated with the change of the immune system and gut microbiota, and the conventional treatments usually result in some side effects. Bifidobacterium longum, as colonizing bacteria in the intestine, has been demonstrated to be capable of relieving colitis in mice and can be employed as an alternative or auxiliary way for treating IBD. Here, the mechanisms of the Bifidobacterium longum in the treatment of IBD were summarized based on previous cell and animal studies and clinical trials testing bacterial therapies. This review will be served as a basis for future research on IBD treatment.http://dx.doi.org/10.1155/2021/8030297 |
| spellingShingle | Shunyu Yao Zixi Zhao Weijun Wang Xiaolu Liu Bifidobacterium Longum: Protection against Inflammatory Bowel Disease Journal of Immunology Research |
| title | Bifidobacterium Longum: Protection against Inflammatory Bowel Disease |
| title_full | Bifidobacterium Longum: Protection against Inflammatory Bowel Disease |
| title_fullStr | Bifidobacterium Longum: Protection against Inflammatory Bowel Disease |
| title_full_unstemmed | Bifidobacterium Longum: Protection against Inflammatory Bowel Disease |
| title_short | Bifidobacterium Longum: Protection against Inflammatory Bowel Disease |
| title_sort | bifidobacterium longum protection against inflammatory bowel disease |
| url | http://dx.doi.org/10.1155/2021/8030297 |
| work_keys_str_mv | AT shunyuyao bifidobacteriumlongumprotectionagainstinflammatoryboweldisease AT zixizhao bifidobacteriumlongumprotectionagainstinflammatoryboweldisease AT weijunwang bifidobacteriumlongumprotectionagainstinflammatoryboweldisease AT xiaoluliu bifidobacteriumlongumprotectionagainstinflammatoryboweldisease |