Basic implications on three pathways associated with SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts between the host and virus and govern induction, resulting in multiorgan impacts. Its pathophysiology involves the followings: 1) the angiotensin-converting enzyme (ACE2) and Toll-like receptor (TLR) pathways: 2) the neuropilin (...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-04-01
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| Series: | Biomedical Journal |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2319417024000696 |
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| author | Jong hoon Lee Consolato Sergi Richard E. Kast Badar A. Kanwar Jean Bourbeau Sangsuk Oh Mun-Gi Sohn Chul Joong Lee Michael D. Coleman |
| author_facet | Jong hoon Lee Consolato Sergi Richard E. Kast Badar A. Kanwar Jean Bourbeau Sangsuk Oh Mun-Gi Sohn Chul Joong Lee Michael D. Coleman |
| author_sort | Jong hoon Lee |
| collection | DOAJ |
| description | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts between the host and virus and govern induction, resulting in multiorgan impacts. Its pathophysiology involves the followings: 1) the angiotensin-converting enzyme (ACE2) and Toll-like receptor (TLR) pathways: 2) the neuropilin (NRP) pathway: 3) the spike protein pathway. Therefore, it is necessary to block the pathological course with modulating innate lymphoid cells against diverse corona variants in the future. |
| format | Article |
| id | doaj-art-14aa8d482d734c479ac979d4dfa24aa7 |
| institution | OA Journals |
| issn | 2319-4170 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biomedical Journal |
| spelling | doaj-art-14aa8d482d734c479ac979d4dfa24aa72025-08-20T02:31:05ZengElsevierBiomedical Journal2319-41702025-04-0148210076610.1016/j.bj.2024.100766Basic implications on three pathways associated with SARS-CoV-2Jong hoon Lee0Consolato Sergi1Richard E. Kast2Badar A. Kanwar3Jean Bourbeau4Sangsuk Oh5Mun-Gi Sohn6Chul Joong Lee7Michael D. Coleman8Science and Research Center, Seoul National University College of Medicine, Seoul, South Korea; Corresponding author. Gyeonggi Medical Center Pocheon Hospital, Department of Geriatrics, 1648 Pocheon-ro, Pocheon-si, Gyeonggi-do, 11142 (Sin-eup-dong), South Korea.Division of Anatomical Pathology, Children's Hospital of Eastern Ontario (CHEO), University of Ottawa, Ottawa, ON, CanadaIIAIGC Study Center, Burlington, VT, USAHaider Associates, Bedford, TX, USARespiratory Epidemiology and Clinical Research Unit, McGill University Health Centre, Montréal, QC, CanadaDepartment of Food Engineering, Food Safety Laboratory, Memory Unit, Ewha Womans University, Seoul, South KoreaDepartment of Food Science, KyungHee University College of Life Science, Seoul, South KoreaDepartment of Anesthesiology, Seoul National University Hospital, Seoul, South KoreaCollege of Health and Life Sciences, Aston University, Birmingham, UK; Corresponding author. College of Health and Life Sciences, Aston University, Birmingham, B4 7ET, UK.Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts between the host and virus and govern induction, resulting in multiorgan impacts. Its pathophysiology involves the followings: 1) the angiotensin-converting enzyme (ACE2) and Toll-like receptor (TLR) pathways: 2) the neuropilin (NRP) pathway: 3) the spike protein pathway. Therefore, it is necessary to block the pathological course with modulating innate lymphoid cells against diverse corona variants in the future.http://www.sciencedirect.com/science/article/pii/S2319417024000696ACE2SARS-CoV-2Spike proteinTLRCOVID-19 |
| spellingShingle | Jong hoon Lee Consolato Sergi Richard E. Kast Badar A. Kanwar Jean Bourbeau Sangsuk Oh Mun-Gi Sohn Chul Joong Lee Michael D. Coleman Basic implications on three pathways associated with SARS-CoV-2 Biomedical Journal ACE2 SARS-CoV-2 Spike protein TLR COVID-19 |
| title | Basic implications on three pathways associated with SARS-CoV-2 |
| title_full | Basic implications on three pathways associated with SARS-CoV-2 |
| title_fullStr | Basic implications on three pathways associated with SARS-CoV-2 |
| title_full_unstemmed | Basic implications on three pathways associated with SARS-CoV-2 |
| title_short | Basic implications on three pathways associated with SARS-CoV-2 |
| title_sort | basic implications on three pathways associated with sars cov 2 |
| topic | ACE2 SARS-CoV-2 Spike protein TLR COVID-19 |
| url | http://www.sciencedirect.com/science/article/pii/S2319417024000696 |
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