Macrophage Changes and High‐Throughput Sequencing in Aging Mouse Intervertebral Disks

Macrophage Changes and High‐Throughput Sequencing in Aging Mouse Intervertebral Disks

ABSTRACT Background Intervertebral disk (IVD) degeneration is associated with lower back pain and aging; however, the mechanisms underlying age‐related changes and the changes in macrophage polarization in aging intervertebral disks require further elucidation. The aim of this study was to evaluate...

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Bibliographic Details
Main Authors: Wei Wang, Cheng Jiang, Jiong‐Hui Chen, Yong‐Long Chen, Zhen‐Wu Zhang, Zhi‐Chao Yang, Jun Li, Xiao‐Chuan Li
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:JOR Spine
Subjects:
high‐throughput sequencing
intervertebral disk
macrophages
senescence
Online Access:https://doi.org/10.1002/jsp2.70061
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