Chronic Lymphocytic Leukemia Presenting as a Subcortical Watershed Infarct

Internal watershed infarcts (WI) involve white matter between deep and superficial arterial systems of middle cerebral artery. These infarcts are considered to be either from low blood flow or microembolism. Anemia is an extremely rare cause of watershed infarcts. Very few cases of hemolytic anemia...

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Main Authors: Mridul Gupta, Divita Singh, Patrick Lee, Sandhya Kadiyam
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2019/2089359
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author Mridul Gupta
Divita Singh
Patrick Lee
Sandhya Kadiyam
author_facet Mridul Gupta
Divita Singh
Patrick Lee
Sandhya Kadiyam
author_sort Mridul Gupta
collection DOAJ
description Internal watershed infarcts (WI) involve white matter between deep and superficial arterial systems of middle cerebral artery. These infarcts are considered to be either from low blood flow or microembolism. Anemia is an extremely rare cause of watershed infarcts. Very few cases of hemolytic anemia causing watershed cerebral infarcts have been reported. Chronic lymphocytic leukemia (CLL) is frequently complicated with secondary autoimmune cytopenia such as autoimmune hemolytic anemia (AIHA), immune thrombocytopenia (ITP), and pure red cell aplasia. AIHA is present in about 7–10% of patients with CLL. AIHA from CLL presenting as WI is an extremely rare phenomenon with no previously published case reports to the best of our knowledge.
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series Case Reports in Hematology
spelling doaj-art-14a65bfb73b445979ca804cebdfa285a2025-08-20T03:54:29ZengWileyCase Reports in Hematology2090-65602090-65792019-01-01201910.1155/2019/20893592089359Chronic Lymphocytic Leukemia Presenting as a Subcortical Watershed InfarctMridul Gupta0Divita Singh1Patrick Lee2Sandhya Kadiyam3Internal Medicine, Monmouth Medical Center, Long Branch, New Jersey, USAAmbulatory Care Pharmacy Resident, University of Florida, Gainesville, Florida, USAHematology and Oncology, Monmouth Medical Center, Long Branch, New Jersey, USAInternal Medicine, Monmouth Medical Center, Long Branch, New Jersey, USAInternal watershed infarcts (WI) involve white matter between deep and superficial arterial systems of middle cerebral artery. These infarcts are considered to be either from low blood flow or microembolism. Anemia is an extremely rare cause of watershed infarcts. Very few cases of hemolytic anemia causing watershed cerebral infarcts have been reported. Chronic lymphocytic leukemia (CLL) is frequently complicated with secondary autoimmune cytopenia such as autoimmune hemolytic anemia (AIHA), immune thrombocytopenia (ITP), and pure red cell aplasia. AIHA is present in about 7–10% of patients with CLL. AIHA from CLL presenting as WI is an extremely rare phenomenon with no previously published case reports to the best of our knowledge.http://dx.doi.org/10.1155/2019/2089359
spellingShingle Mridul Gupta
Divita Singh
Patrick Lee
Sandhya Kadiyam
Chronic Lymphocytic Leukemia Presenting as a Subcortical Watershed Infarct
Case Reports in Hematology
title Chronic Lymphocytic Leukemia Presenting as a Subcortical Watershed Infarct
title_full Chronic Lymphocytic Leukemia Presenting as a Subcortical Watershed Infarct
title_fullStr Chronic Lymphocytic Leukemia Presenting as a Subcortical Watershed Infarct
title_full_unstemmed Chronic Lymphocytic Leukemia Presenting as a Subcortical Watershed Infarct
title_short Chronic Lymphocytic Leukemia Presenting as a Subcortical Watershed Infarct
title_sort chronic lymphocytic leukemia presenting as a subcortical watershed infarct
url http://dx.doi.org/10.1155/2019/2089359
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AT divitasingh chroniclymphocyticleukemiapresentingasasubcorticalwatershedinfarct
AT patricklee chroniclymphocyticleukemiapresentingasasubcorticalwatershedinfarct
AT sandhyakadiyam chroniclymphocyticleukemiapresentingasasubcorticalwatershedinfarct