PULMONARY SARCOIDOSIS WITH BONE INVOLVEMENT MIMICKING METASTATIC CANCER
Sarcoidosis is a disease of unknown etiology which can affect the lungs and lymph nodes, skin, eyes and other organs and, in rare cases, bones and bone marrow cells. We present a case of a 39-year-old male patient with an iliac bone involvement of sarcoidosis mimicking malignancy. Lymphoma and metas...
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| Language: | English |
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Istanbul University Press
2022-01-01
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| Series: | İstanbul Tıp Fakültesi Dergisi |
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| Online Access: | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/5508CD08EACD428E9DB884B4F9BC7E30 |
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| author | Ece Şahinoğlu Ahmet Hamdi Ilgazlı |
| author_facet | Ece Şahinoğlu Ahmet Hamdi Ilgazlı |
| author_sort | Ece Şahinoğlu |
| collection | DOAJ |
| description | Sarcoidosis is a disease of unknown etiology which can affect the lungs and lymph nodes, skin, eyes and other organs and, in rare cases, bones and bone marrow cells. We present a case of a 39-year-old male patient with an iliac bone involvement of sarcoidosis mimicking malignancy. Lymphoma and metastatic cancer proved a challenge to discard in differential diagnosis. He underwent multiple biopsies including tru-cut lung parenchyma and iliac bone biopsies. All of the biopsy specimens were reported as non-necrotising granulomatous inflammation. He underwent corticosteroid treatment. His response to the steroid treatment was insufficient so methotrexate was added to the corticosteroid therapy. Afterwards, clinical and radiological improvement was recorded. We aimed to highlight the utilization of taking new biopsies and histopathological re-evaluations in order to confirm the diagnosis and distinguish a benign disease from a malignant one. |
| format | Article |
| id | doaj-art-1495d791d8e34dd99c13e51a470fcf82 |
| institution | OA Journals |
| issn | 1305-6441 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Istanbul University Press |
| record_format | Article |
| series | İstanbul Tıp Fakültesi Dergisi |
| spelling | doaj-art-1495d791d8e34dd99c13e51a470fcf822025-08-20T02:15:19ZengIstanbul University Pressİstanbul Tıp Fakültesi Dergisi1305-64412022-01-0185112512910.26650/IUITFD.853034123456PULMONARY SARCOIDOSIS WITH BONE INVOLVEMENT MIMICKING METASTATIC CANCEREce Şahinoğlu0https://orcid.org/0000-0002-3422-6433Ahmet Hamdi Ilgazlı1https://orcid.org/0000-0001-9017-2014Kocaeli Üniversitesi, Kocaeli, TürkiyeKocaeli Üniversitesi, Kocaeli, TürkiyeSarcoidosis is a disease of unknown etiology which can affect the lungs and lymph nodes, skin, eyes and other organs and, in rare cases, bones and bone marrow cells. We present a case of a 39-year-old male patient with an iliac bone involvement of sarcoidosis mimicking malignancy. Lymphoma and metastatic cancer proved a challenge to discard in differential diagnosis. He underwent multiple biopsies including tru-cut lung parenchyma and iliac bone biopsies. All of the biopsy specimens were reported as non-necrotising granulomatous inflammation. He underwent corticosteroid treatment. His response to the steroid treatment was insufficient so methotrexate was added to the corticosteroid therapy. Afterwards, clinical and radiological improvement was recorded. We aimed to highlight the utilization of taking new biopsies and histopathological re-evaluations in order to confirm the diagnosis and distinguish a benign disease from a malignant one.https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/5508CD08EACD428E9DB884B4F9BC7E30sarcoidosisdifferential diagnosismalignancy |
| spellingShingle | Ece Şahinoğlu Ahmet Hamdi Ilgazlı PULMONARY SARCOIDOSIS WITH BONE INVOLVEMENT MIMICKING METASTATIC CANCER İstanbul Tıp Fakültesi Dergisi sarcoidosis differential diagnosis malignancy |
| title | PULMONARY SARCOIDOSIS WITH BONE INVOLVEMENT MIMICKING METASTATIC CANCER |
| title_full | PULMONARY SARCOIDOSIS WITH BONE INVOLVEMENT MIMICKING METASTATIC CANCER |
| title_fullStr | PULMONARY SARCOIDOSIS WITH BONE INVOLVEMENT MIMICKING METASTATIC CANCER |
| title_full_unstemmed | PULMONARY SARCOIDOSIS WITH BONE INVOLVEMENT MIMICKING METASTATIC CANCER |
| title_short | PULMONARY SARCOIDOSIS WITH BONE INVOLVEMENT MIMICKING METASTATIC CANCER |
| title_sort | pulmonary sarcoidosis with bone involvement mimicking metastatic cancer |
| topic | sarcoidosis differential diagnosis malignancy |
| url | https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/5508CD08EACD428E9DB884B4F9BC7E30 |
| work_keys_str_mv | AT ecesahinoglu pulmonarysarcoidosiswithboneinvolvementmimickingmetastaticcancer AT ahmethamdiilgazlı pulmonarysarcoidosiswithboneinvolvementmimickingmetastaticcancer |