Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity

Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity

Abstract Feline diffuse iris melanoma (FDIM) is the most common primary ocular tumour in cats, with metastatic disease occurring in 19–63% of patients. Greater intraocular invasion correlates with increased mortality. No effective therapeutics exist for metastatic FDIM, partly due to a lack of known...

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Bibliographic Details
Main Authors: D. Kayes, B. Blacklock, R. McGeachan, E. Scurrell, K. Donnelly, L. Murphy, A. Fawkes, R. Clark, A. Meynert, H. Becher, R. Pittaway, G. Fricker, R. Tetas Pont, A. Suárez-Bonnet, K. L. Bowlt Blacklock
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Feline diffuse iris melanoma
Melanoma metastasis
Transcriptome
Gene expression
Uveal melanoma
Online Access:https://doi.org/10.1038/s41598-025-09632-5
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