A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ Ivoire

Cryptococcosis is an opportunistic mycosis caused by Cryptococcus, mainly affecting the immunocompromised. We report a case of pulmonary cryptococcosis within a 31-year-old immunocompetent patient admitted for painful chest swelling evolving for 4 months prior to admission. The chest X-Ray showed a...

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Main Authors: Ahou Sandrine Konan, Kalou Dibert Zika, Affoué Sandrine Josette Kouakou, Appi Sandrine Kouamé, Malick Senanminfoun Soro, Koffi Daho Adoubryn
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Medical Mycology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211753925000107
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author Ahou Sandrine Konan
Kalou Dibert Zika
Affoué Sandrine Josette Kouakou
Appi Sandrine Kouamé
Malick Senanminfoun Soro
Koffi Daho Adoubryn
author_facet Ahou Sandrine Konan
Kalou Dibert Zika
Affoué Sandrine Josette Kouakou
Appi Sandrine Kouamé
Malick Senanminfoun Soro
Koffi Daho Adoubryn
author_sort Ahou Sandrine Konan
collection DOAJ
description Cryptococcosis is an opportunistic mycosis caused by Cryptococcus, mainly affecting the immunocompromised. We report a case of pulmonary cryptococcosis within a 31-year-old immunocompetent patient admitted for painful chest swelling evolving for 4 months prior to admission. The chest X-Ray showed a rounded pulmonary opacity. The chest ultrasound revealed a pulmonary abscess diffusing under the skin. Direct examination using the Indian ink and the May-Grunwald Giemsa staining revealed encapsulated yeasts in the pus. The Culture of the pus on the Sabouraud medium with chloramphenicol confirmed the presence of Cryptococcus neoformans. Cryptococcal antigen was positive. This case reminds us that cryptococcosis should be considered even without immunosuppression.
format Article
id doaj-art-148a1e501b774be5989dfa04341feb0f
institution Kabale University
issn 2211-7539
language English
publishDate 2025-06-01
publisher Elsevier
record_format Article
series Medical Mycology Case Reports
spelling doaj-art-148a1e501b774be5989dfa04341feb0f2025-08-20T03:45:28ZengElsevierMedical Mycology Case Reports2211-75392025-06-014810070110.1016/j.mmcr.2025.100701A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ IvoireAhou Sandrine Konan0Kalou Dibert Zika1Affoué Sandrine Josette Kouakou2Appi Sandrine Kouamé3Malick Senanminfoun Soro4Koffi Daho Adoubryn5Parasitology-Mycology Laboratory, Teaching Hospital University of Bouake, 01 BP 1174 Bouake 01, Cote d'Ivoire; School of Medicine, Alassane Ouattara University, BPV 18 Bouake, Cote d'Ivoire; Corresponding author. Parasitology-Mycology Laboratory, Teaching Hospital University of Bouake, 01 BP 1174 Bouake 01, Cote d'Ivoire.Parasitology-Mycology Laboratory, Teaching Hospital University of Bouake, 01 BP 1174 Bouake 01, Cote d'Ivoire; School of Medicine, Alassane Ouattara University, BPV 18 Bouake, Cote d'IvoireParasitology-Mycology Laboratory, Teaching Hospital University of Bouake, 01 BP 1174 Bouake 01, Cote d'Ivoire; School of Medicine, Alassane Ouattara University, BPV 18 Bouake, Cote d'IvoireParasitology-Mycology Laboratory, Teaching Hospital University of Bouake, 01 BP 1174 Bouake 01, Cote d'IvoireImaging Department, Teaching Hospital University of Bouake, 01 BP 1174 Bouake 01, Cote d'IvoireParasitology-Mycology Laboratory, Teaching Hospital University of Bouake, 01 BP 1174 Bouake 01, Cote d'Ivoire; School of Medicine, Alassane Ouattara University, BPV 18 Bouake, Cote d'IvoireCryptococcosis is an opportunistic mycosis caused by Cryptococcus, mainly affecting the immunocompromised. We report a case of pulmonary cryptococcosis within a 31-year-old immunocompetent patient admitted for painful chest swelling evolving for 4 months prior to admission. The chest X-Ray showed a rounded pulmonary opacity. The chest ultrasound revealed a pulmonary abscess diffusing under the skin. Direct examination using the Indian ink and the May-Grunwald Giemsa staining revealed encapsulated yeasts in the pus. The Culture of the pus on the Sabouraud medium with chloramphenicol confirmed the presence of Cryptococcus neoformans. Cryptococcal antigen was positive. This case reminds us that cryptococcosis should be considered even without immunosuppression.http://www.sciencedirect.com/science/article/pii/S2211753925000107CryptococcosisLungCryptococcus neoformansImmunocompetentCote d’Ivoire
spellingShingle Ahou Sandrine Konan
Kalou Dibert Zika
Affoué Sandrine Josette Kouakou
Appi Sandrine Kouamé
Malick Senanminfoun Soro
Koffi Daho Adoubryn
A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ Ivoire
Medical Mycology Case Reports
Cryptococcosis
Lung
Cryptococcus neoformans
Immunocompetent
Cote d’Ivoire
title A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ Ivoire
title_full A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ Ivoire
title_fullStr A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ Ivoire
title_full_unstemmed A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ Ivoire
title_short A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ Ivoire
title_sort fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from cote d ivoire
topic Cryptococcosis
Lung
Cryptococcus neoformans
Immunocompetent
Cote d’Ivoire
url http://www.sciencedirect.com/science/article/pii/S2211753925000107
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